Pediatric lupus nephritis

Involvement of the kidneys by lupus nephritis (LN) is one of the most severe clinical manifestations seen in individuals with systemic lupus erythematosus (SLE). LN is more frequent and severe in pediatric patients and has been associated with higher morbidity and mortality rates. This narrative rev...

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Detalles Bibliográficos
Autores principales: Pinheiro, Sergio Veloso Brant, Dias, Raphael Figuiredo, Fabiano, Rafaela Cabral Gonçalves, Araujo, Stanley de Almeida, Silva, Ana Cristina Simões e
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Nefrologia 2018
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699445/
https://www.ncbi.nlm.nih.gov/pubmed/30465590
http://dx.doi.org/10.1590/2175-8239-JBN-2018-0097
Descripción
Sumario:Involvement of the kidneys by lupus nephritis (LN) is one of the most severe clinical manifestations seen in individuals with systemic lupus erythematosus (SLE). LN is more frequent and severe in pediatric patients and has been associated with higher morbidity and mortality rates. This narrative review aimed to describe the general aspects of LN and its particularities when affecting children and adolescents, while focusing on the disease's etiopathogenesis, clinical manifestations, renal tissue alterations, and treatment options.

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