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Retinal angiographic alteration in diabetic macular edema after dexamethasone implantation: a case report
Here we reported a rare case of the implantation of a dexamethasone intravitreal implant (DEX) in which decreased retinal vessel density (VD) was found by optical coherence tomography angiography (OCTA). A 74-year-old male with diabetes mellitus presented with bilateral macular edema. The best-corre...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699512/ https://www.ncbi.nlm.nih.gov/pubmed/31616191 http://dx.doi.org/10.2147/IMCRJ.S214414 |
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author | Lee, Chia-Yi Ching, Cheng-Chao Sun, Chi-Chin Chen, Hung-Chi Lin, Hung-Yu |
author_facet | Lee, Chia-Yi Ching, Cheng-Chao Sun, Chi-Chin Chen, Hung-Chi Lin, Hung-Yu |
author_sort | Lee, Chia-Yi |
collection | PubMed |
description | Here we reported a rare case of the implantation of a dexamethasone intravitreal implant (DEX) in which decreased retinal vessel density (VD) was found by optical coherence tomography angiography (OCTA). A 74-year-old male with diabetes mellitus presented with bilateral macular edema. The best-corrected visual acuity (BCVA) was 0.6 in the right eye. Diabetic macular edema (DME) was diagnosed. A DEX for the right eye was planned, and the preoperative evaluation showed a superficial VD of 48.74 percent, a deep VD of 53.12 percent, and a foveal avascular zone (FAZ) 0.165 mm(2) in size by OCTA. The BCVA in the right eye recovered to 0.8, and a notably lower superficial VD of 45.97 percent and a deep VD of 45.40 percent were observed with an enlarged FAZ of 0.294 mm(2) one month postoperatively. Moreover, BCVA in the right eye was maintained at 0.8, while further reductions in both superficial (40.07 percent) and deep (40.91 percent) VD were noted with a FAZ measured at 0.305 mm(2) two months postoperatively. In conclusion, retinal superficial and deep VD decreased, while the FAZ increased, after the implantation of the DEX in a patient with DME. |
format | Online Article Text |
id | pubmed-6699512 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-66995122019-10-15 Retinal angiographic alteration in diabetic macular edema after dexamethasone implantation: a case report Lee, Chia-Yi Ching, Cheng-Chao Sun, Chi-Chin Chen, Hung-Chi Lin, Hung-Yu Int Med Case Rep J Case Report Here we reported a rare case of the implantation of a dexamethasone intravitreal implant (DEX) in which decreased retinal vessel density (VD) was found by optical coherence tomography angiography (OCTA). A 74-year-old male with diabetes mellitus presented with bilateral macular edema. The best-corrected visual acuity (BCVA) was 0.6 in the right eye. Diabetic macular edema (DME) was diagnosed. A DEX for the right eye was planned, and the preoperative evaluation showed a superficial VD of 48.74 percent, a deep VD of 53.12 percent, and a foveal avascular zone (FAZ) 0.165 mm(2) in size by OCTA. The BCVA in the right eye recovered to 0.8, and a notably lower superficial VD of 45.97 percent and a deep VD of 45.40 percent were observed with an enlarged FAZ of 0.294 mm(2) one month postoperatively. Moreover, BCVA in the right eye was maintained at 0.8, while further reductions in both superficial (40.07 percent) and deep (40.91 percent) VD were noted with a FAZ measured at 0.305 mm(2) two months postoperatively. In conclusion, retinal superficial and deep VD decreased, while the FAZ increased, after the implantation of the DEX in a patient with DME. Dove 2019-08-15 /pmc/articles/PMC6699512/ /pubmed/31616191 http://dx.doi.org/10.2147/IMCRJ.S214414 Text en © 2019 Lee et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Case Report Lee, Chia-Yi Ching, Cheng-Chao Sun, Chi-Chin Chen, Hung-Chi Lin, Hung-Yu Retinal angiographic alteration in diabetic macular edema after dexamethasone implantation: a case report |
title | Retinal angiographic alteration in diabetic macular edema after dexamethasone implantation: a case report |
title_full | Retinal angiographic alteration in diabetic macular edema after dexamethasone implantation: a case report |
title_fullStr | Retinal angiographic alteration in diabetic macular edema after dexamethasone implantation: a case report |
title_full_unstemmed | Retinal angiographic alteration in diabetic macular edema after dexamethasone implantation: a case report |
title_short | Retinal angiographic alteration in diabetic macular edema after dexamethasone implantation: a case report |
title_sort | retinal angiographic alteration in diabetic macular edema after dexamethasone implantation: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699512/ https://www.ncbi.nlm.nih.gov/pubmed/31616191 http://dx.doi.org/10.2147/IMCRJ.S214414 |
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