TKI-resistant ALK-rearranged lung adenocarcinoma with secondary CTNNB1 p.S45V and tertiary ALK p.I1171N mutations

Anaplastic lymphoma kinase (ALK)-rearranged non-small cell lung cancer (NSCLC) is an important molecular subgroup of tumors that are typically sensitive to tyrosine kinase inhibitors (TKIs). Although a substantial portion of patients benefit from TKIs, this approach is complicated by intrinsic and a...

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Detalles Bibliográficos
Autores principales: Ouseph, Madhu M, Taber, Angela, Khurshid, Humera, Madison, Russell, Aswad, Bassam I, Resnick, Murray B, Yakirevich, Evgeny, Ali, Siraj M, Patel, Nimesh R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699522/
https://www.ncbi.nlm.nih.gov/pubmed/31616196
http://dx.doi.org/10.2147/LCTT.S212406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699522/
https://www.ncbi.nlm.nih.gov/pubmed/31616196
http://dx.doi.org/10.2147/LCTT.S212406

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