Cargando…
CHAP: A Versatile Tool for the Structural and Functional Annotation of Ion Channel Pores
The control of ion channel permeation requires the modulation of energetic barriers or “gates” within their pores. However, such barriers are often simply identified from the physical dimensions of the pore. Such approaches have worked well in the past, but there is now evidence that the unusual beh...
Autores principales: | Klesse, Gianni, Rao, Shanlin, Sansom, Mark S.P., Tucker, Stephen J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699600/ https://www.ncbi.nlm.nih.gov/pubmed/31220459 http://dx.doi.org/10.1016/j.jmb.2019.06.003 |
Ejemplares similares
-
A BEST example of channel structure annotation by molecular simulation
por: Rao, Shanlin, et al.
Publicado: (2017) -
Functional Annotation of Ion Channel Structures by Molecular Simulation
por: Trick, Jemma L., et al.
Publicado: (2016) -
Induced
Polarization in Molecular Dynamics Simulations
of the 5-HT(3) Receptor Channel
por: Klesse, Gianni, et al.
Publicado: (2020) -
A heuristic derived from analysis of the ion channel structural proteome permits the rapid identification of hydrophobic gates
por: Rao, Shanlin, et al.
Publicado: (2019) -
Molecular Simulations of Hydrophobic Gating of Pentameric
Ligand Gated Ion Channels: Insights into Water and Ions
por: Rao, Shanlin, et al.
Publicado: (2021)