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Cardiometabolic risk factor levels in Norwegian children compared to international reference values: The ASK study

OBJECTIVE: To investigate cardiometabolic risk factor levels in a group of Norwegian 10-year-old children compared to international values and examine the association between cardiorespiratory fitness (CRF) and the reference-standardized clustered risk score. METHODS: 913 children (49% girls) were i...

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Autores principales: Stavnsbo, Mette, Skrede, Turid, Aadland, Eivind, Aadland, Katrine N., Chinapaw, Mai, Anderssen, Sigmund A., Andersen, Lars B., Resaland, Geir K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699667/
https://www.ncbi.nlm.nih.gov/pubmed/31425532
http://dx.doi.org/10.1371/journal.pone.0220239
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author Stavnsbo, Mette
Skrede, Turid
Aadland, Eivind
Aadland, Katrine N.
Chinapaw, Mai
Anderssen, Sigmund A.
Andersen, Lars B.
Resaland, Geir K.
author_facet Stavnsbo, Mette
Skrede, Turid
Aadland, Eivind
Aadland, Katrine N.
Chinapaw, Mai
Anderssen, Sigmund A.
Andersen, Lars B.
Resaland, Geir K.
author_sort Stavnsbo, Mette
collection PubMed
description OBJECTIVE: To investigate cardiometabolic risk factor levels in a group of Norwegian 10-year-old children compared to international values and examine the association between cardiorespiratory fitness (CRF) and the reference-standardized clustered risk score. METHODS: 913 children (49% girls) were included from the Active Smarter Kids (ASK) study. Body mass index (BMI), waist circumference (WC), systolic blood pressure (SBP), diastolic blood pressure (DBP), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), total cholesterol (TC) to HDL-C ratio, triglyceride (TG), glucose, insulin, homeostatic model assessment (HOMA) score and CRF, were standardized according to international age-and sex-specific reference values. RESULTS: The Norwegian children had significantly more favorable WC, DBP, glucose, HDL-C and CRF levels compared to the international reference values, but similar or less favorable levels of other cardiometabolic risk factors. CRF was the variable that differed the most from the international values (mean (95% CI) 1.20 (1.16 to 1.24) SD). The clustered risk score (excluding CRF) was higher in the Norwegian children, but decreased to below international levels when including CRF (mean (95% CI) - 0.08 (- 0.12 to –0.05) SD). CRF had a significant inverse association with the clustered risk score (excluding CRF) (β - 0.37 SD, 95% CI –0.43 to –0.31). CONCLUSIONS: Norwegian children have substantially higher CRF levels than international standards, and including CRF in clustered risk scores reduces overall risk in Norwegian children below that of international levels. CRF is associated with improved cardiometabolic health in children.
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spelling pubmed-66996672019-09-04 Cardiometabolic risk factor levels in Norwegian children compared to international reference values: The ASK study Stavnsbo, Mette Skrede, Turid Aadland, Eivind Aadland, Katrine N. Chinapaw, Mai Anderssen, Sigmund A. Andersen, Lars B. Resaland, Geir K. PLoS One Research Article OBJECTIVE: To investigate cardiometabolic risk factor levels in a group of Norwegian 10-year-old children compared to international values and examine the association between cardiorespiratory fitness (CRF) and the reference-standardized clustered risk score. METHODS: 913 children (49% girls) were included from the Active Smarter Kids (ASK) study. Body mass index (BMI), waist circumference (WC), systolic blood pressure (SBP), diastolic blood pressure (DBP), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), total cholesterol (TC) to HDL-C ratio, triglyceride (TG), glucose, insulin, homeostatic model assessment (HOMA) score and CRF, were standardized according to international age-and sex-specific reference values. RESULTS: The Norwegian children had significantly more favorable WC, DBP, glucose, HDL-C and CRF levels compared to the international reference values, but similar or less favorable levels of other cardiometabolic risk factors. CRF was the variable that differed the most from the international values (mean (95% CI) 1.20 (1.16 to 1.24) SD). The clustered risk score (excluding CRF) was higher in the Norwegian children, but decreased to below international levels when including CRF (mean (95% CI) - 0.08 (- 0.12 to –0.05) SD). CRF had a significant inverse association with the clustered risk score (excluding CRF) (β - 0.37 SD, 95% CI –0.43 to –0.31). CONCLUSIONS: Norwegian children have substantially higher CRF levels than international standards, and including CRF in clustered risk scores reduces overall risk in Norwegian children below that of international levels. CRF is associated with improved cardiometabolic health in children. Public Library of Science 2019-08-19 /pmc/articles/PMC6699667/ /pubmed/31425532 http://dx.doi.org/10.1371/journal.pone.0220239 Text en © 2019 Stavnsbo et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Stavnsbo, Mette
Skrede, Turid
Aadland, Eivind
Aadland, Katrine N.
Chinapaw, Mai
Anderssen, Sigmund A.
Andersen, Lars B.
Resaland, Geir K.
Cardiometabolic risk factor levels in Norwegian children compared to international reference values: The ASK study
title Cardiometabolic risk factor levels in Norwegian children compared to international reference values: The ASK study
title_full Cardiometabolic risk factor levels in Norwegian children compared to international reference values: The ASK study
title_fullStr Cardiometabolic risk factor levels in Norwegian children compared to international reference values: The ASK study
title_full_unstemmed Cardiometabolic risk factor levels in Norwegian children compared to international reference values: The ASK study
title_short Cardiometabolic risk factor levels in Norwegian children compared to international reference values: The ASK study
title_sort cardiometabolic risk factor levels in norwegian children compared to international reference values: the ask study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699667/
https://www.ncbi.nlm.nih.gov/pubmed/31425532
http://dx.doi.org/10.1371/journal.pone.0220239
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