Identification of lead molecules against potential drug target protein MAPK4 from L. donovani: An in-silico approach using docking, molecular dynamics and binding free energy calculation

Leishmaniasis caused by obligate intracellular parasites of genus Leishmania is one of the most neglected tropical diseases threatening 350 million people worldwide. Protein kinases have drawn much attention as potential drug targets due to their important role in various cellular processes. In Leis...

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Detalles Bibliográficos
Autores principales: Raj, Shweta, Sasidharan, Santanu, Dubey, Vikash Kumar, Saudagar, Prakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699710/
https://www.ncbi.nlm.nih.gov/pubmed/31425543
http://dx.doi.org/10.1371/journal.pone.0221331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699710/
https://www.ncbi.nlm.nih.gov/pubmed/31425543
http://dx.doi.org/10.1371/journal.pone.0221331

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