Netrin-1 Alters Adipose Tissue Macrophage Fate and Function in Obesity

Macrophages accumulate prominently in the visceral adipose tissue (VAT) of obese humans and high fat diet (HFD) fed mice, and this is linked to insulin resistance and type II diabetes. While the mechanisms regulating macrophage recruitment in obesity have been delineated, the signals directing macro...

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Detalles Bibliográficos
Autores principales: Sharma, Monika, Schlegel, Martin, Brown, Emily J., Sansbury, Brian E., Weinstock, Ada, Afonso, Milessa S., Corr, Emma M., van Solingen, Coen, Shanley, Lianne C., Peled, Daniel, Ramasamy, Ravichandran, Schmidt, Ann Marie, Spite, Matthew, Fisher, Edward A., Moore, Kathryn J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699780/
https://www.ncbi.nlm.nih.gov/pubmed/31428465
http://dx.doi.org/10.20900/immunometab20190010

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