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COMP-Ang1 Stabilizes Hyperglycemic Disruption of Blood-Retinal Barrier Phenotype in Human Retinal Microvascular Endothelial Cells

PURPOSE: Current treatments for diabetic retinopathy (DR) have considerable limitations, underpinning the need for new therapeutic options. In this article, the ability of an engineered angiopoietin-1 variant (COMP-Ang1) to ameliorate the injurious effects of hyperglycemia on barrier integrity in a...

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Detalles Bibliográficos
Autores principales:	Rochfort, Keith D., Carroll, Lara S., Barabas, Peter, Curtis, Timothy M., Ambati, Balamurali K., Barron, Niall, Cummins, Philip M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2019
Materias:	Retinal Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699794/ https://www.ncbi.nlm.nih.gov/pubmed/31415078 http://dx.doi.org/10.1167/iovs.19-27644

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