Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase

The genetically diverse Orthocoronavirinae (CoV) family is prone to cross species transmission and disease emergence in both humans and livestock. Viruses similar to known epidemic strains circulating in wild and domestic animals further increase the probability of emergence in the future. Currently...

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Detalles Bibliográficos
Autores principales: Brown, Ariane J., Won, John J., Graham, Rachel L., Dinnon, Kenneth H., Sims, Amy C., Feng, Joy Y., Cihlar, Tomas, Denison, Mark R., Baric, Ralph S., Sheahan, Timothy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699884/
https://www.ncbi.nlm.nih.gov/pubmed/31233808
http://dx.doi.org/10.1016/j.antiviral.2019.104541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699884/
https://www.ncbi.nlm.nih.gov/pubmed/31233808
http://dx.doi.org/10.1016/j.antiviral.2019.104541

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