Development of blastocyst complementation technology without contributions to gametes and the brain

In Japan, it is possible to generate chimeric animals from specified embryos by combining animal blastocysts with human pluripotent stem (PS) cells (animal-human PS chimera). However, the production of animal-human PS chimeras has been restricted because of ethical concerns, such as the development...

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Detalles Bibliográficos
Autores principales: Hashimoto, Haruo, Eto, Tomoo, Yamamoto, Masafumi, Yagoto, Mika, Goto, Motohito, Kagawa, Takahiro, Kojima, Keisuke, Kawai, Kenji, Akimoto, Toshio, Takahashi, Ri-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2019
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699975/
https://www.ncbi.nlm.nih.gov/pubmed/30996149
http://dx.doi.org/10.1538/expanim.18-0173

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