Multi-Compartment Profiling of Bacterial and Host Metabolites Identifies Intestinal Dysbiosis and Its Functional Consequences in the Critically Ill Child

OBJECTIVES: Adverse physiology and antibiotic exposure devastate the intestinal microbiome in critical illness. Time and cost implications limit the immediate clinical potential of microbial sequencing to identify or treat intestinal dysbiosis. Here, we examined whether metabolic profiling is a feas...

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Detalles Bibliográficos
Autores principales: Wijeyesekera, Anisha, Wagner, Josef, De Goffau, Marcus, Thurston, Sarah, Rodrigues Sabino, Adilson, Zaher, Sara, White, Deborah, Ridout, Jenna, Peters, Mark J., Ramnarayan, Padmanabhan, Branco, Ricardo G., Torok, M. Estee, Valla, Frederic, Meyer, Rosan, Klein, Nigel, Frost, Gary, Parkhill, Julian, Holmes, Elaine, Pathan, Nazima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Online Clinical Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699985/
https://www.ncbi.nlm.nih.gov/pubmed/31169619
http://dx.doi.org/10.1097/CCM.0000000000003841

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