NudC-like protein 2 restrains centriole amplification by stabilizing HERC2

Centriole duplication is tightly controlled to occur once per cell cycle, and disruption of this synchrony causes centriole amplification, which is frequently observed in many cancers. Our previous work showed that nuclear distribution gene C (NudC)-like protein 2 (NudCL2) localizes to centrosomes;...

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Detalles Bibliográficos
Autores principales: Li, Min, Xu, Xiaoyang, Zhang, Jun, Liu, Min, Wang, Wei, Gao, Ya, Sun, Qiang, Zhang, Jiayu, Lu, Yunkun, Wang, Fangwei, Liu, Wei, Zhou, Tianhua, Yang, Yuehong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700069/
https://www.ncbi.nlm.nih.gov/pubmed/31427565
http://dx.doi.org/10.1038/s41419-019-1843-3

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