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Citrullination facilitates cross-reactivity of rheumatoid factor with non-IgG1 Fc epitopes in rheumatoid arthritis

Rheumatoid factor (RF) and anti-citrullinated protein antibodies (ACPAs) are the two most prevalent autoantibodies in rheumatoid arthritis (RA), and are thought to have distinct autoantigen targets. Whilst RF targets the Fc region of antibodies, ACPAs target a far broader spectrum of citrullinated p...

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Detalles Bibliográficos
Autores principales:	Trela, Malgorzata, Perera, Shantha, Sheeran, Thomas, Rylance, Paul, Nelson, Paul N., Attridge, Kesley
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700074/ https://www.ncbi.nlm.nih.gov/pubmed/31427662 http://dx.doi.org/10.1038/s41598-019-48176-3

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