Efficacy of TIMOLOL nasal spray as a treatment for epistaxis in hereditary hemorrhagic telangiectasia. A double-blind, randomized, placebo-controlled trial

Hereditary hemorrhagic telangiectasia is a rare vascular genetic disease. Epistaxis is the most frequent and disabling manifestation, and timolol appears to be a new therapeutic option as non-selective beta-blockers have in vitro and in vivo anti-angiogenic properties. Our main objective was to eval...

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Detalles Bibliográficos
Autores principales: Dupuis-Girod, Sophie, Pitiot, Vincent, Bergerot, Cyrille, Fargeton, Anne-Emmanuelle, Beaudoin, Marjolaine, Decullier, Evelyne, Bréant, Valentine, Colombet, Bettina, Philouze, Pierre, Faure, Frédéric, Letievant, Jean-Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700077/
https://www.ncbi.nlm.nih.gov/pubmed/31427745
http://dx.doi.org/10.1038/s41598-019-48502-9

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