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Regular exercise improves asthma control in adults: A randomized controlled trial
We conducted a randomized controlled trial to test the hypothesis that a 24-week exercise intervention improves asthma control in adults. Adults with mild or moderate asthma were randomly assigned to either the exercise intervention group (IG) or the reference group (RG). Participants in IG received...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700123/ https://www.ncbi.nlm.nih.gov/pubmed/31427628 http://dx.doi.org/10.1038/s41598-019-48484-8 |
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author | Jaakkola, Jouni J. K. Aalto, Sirpa A. M. Hernberg, Samu Kiihamäki, Simo-Pekka Jaakkola, Maritta S. |
author_facet | Jaakkola, Jouni J. K. Aalto, Sirpa A. M. Hernberg, Samu Kiihamäki, Simo-Pekka Jaakkola, Maritta S. |
author_sort | Jaakkola, Jouni J. K. |
collection | PubMed |
description | We conducted a randomized controlled trial to test the hypothesis that a 24-week exercise intervention improves asthma control in adults. Adults with mild or moderate asthma were randomly assigned to either the exercise intervention group (IG) or the reference group (RG). Participants in IG received an individualized exercising program, including aerobic exercise at least three times a week for ≥30 minutes, muscle training, and stretching. The primary outcome was asthma control, measured by Asthma Control Test (ACT), asthma-related symptoms, and peak expiratory flow (PEF) variability. We estimated the risk (i.e. probability) of improvement in asthma control and the risk difference (RD) between IG and RG. Of 131 subjects (67 IG/64 RG) entered, 105 subjects (51/54) completed the trial (80%), and 89 (44/45) were analysed (68%). The ACT became better among 26 (62%) participants in IG and among 17 (39%) participants in RG. The effect of intervention on improving asthma control was 23% (RD = 0.23, 95% CI 0.027–0.438; P = 0.0320). The intervention also reduced shortness of breath by 30.1% (RD = 0.301, 95% CI 0.109–0.492; P = 0.003). The change in PEF variability was similar in both groups. Regular exercise improves asthma control measured by the ACT, while has little effect on PEF variability. |
format | Online Article Text |
id | pubmed-6700123 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-67001232019-08-21 Regular exercise improves asthma control in adults: A randomized controlled trial Jaakkola, Jouni J. K. Aalto, Sirpa A. M. Hernberg, Samu Kiihamäki, Simo-Pekka Jaakkola, Maritta S. Sci Rep Article We conducted a randomized controlled trial to test the hypothesis that a 24-week exercise intervention improves asthma control in adults. Adults with mild or moderate asthma were randomly assigned to either the exercise intervention group (IG) or the reference group (RG). Participants in IG received an individualized exercising program, including aerobic exercise at least three times a week for ≥30 minutes, muscle training, and stretching. The primary outcome was asthma control, measured by Asthma Control Test (ACT), asthma-related symptoms, and peak expiratory flow (PEF) variability. We estimated the risk (i.e. probability) of improvement in asthma control and the risk difference (RD) between IG and RG. Of 131 subjects (67 IG/64 RG) entered, 105 subjects (51/54) completed the trial (80%), and 89 (44/45) were analysed (68%). The ACT became better among 26 (62%) participants in IG and among 17 (39%) participants in RG. The effect of intervention on improving asthma control was 23% (RD = 0.23, 95% CI 0.027–0.438; P = 0.0320). The intervention also reduced shortness of breath by 30.1% (RD = 0.301, 95% CI 0.109–0.492; P = 0.003). The change in PEF variability was similar in both groups. Regular exercise improves asthma control measured by the ACT, while has little effect on PEF variability. Nature Publishing Group UK 2019-08-19 /pmc/articles/PMC6700123/ /pubmed/31427628 http://dx.doi.org/10.1038/s41598-019-48484-8 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Jaakkola, Jouni J. K. Aalto, Sirpa A. M. Hernberg, Samu Kiihamäki, Simo-Pekka Jaakkola, Maritta S. Regular exercise improves asthma control in adults: A randomized controlled trial |
title | Regular exercise improves asthma control in adults: A randomized controlled trial |
title_full | Regular exercise improves asthma control in adults: A randomized controlled trial |
title_fullStr | Regular exercise improves asthma control in adults: A randomized controlled trial |
title_full_unstemmed | Regular exercise improves asthma control in adults: A randomized controlled trial |
title_short | Regular exercise improves asthma control in adults: A randomized controlled trial |
title_sort | regular exercise improves asthma control in adults: a randomized controlled trial |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700123/ https://www.ncbi.nlm.nih.gov/pubmed/31427628 http://dx.doi.org/10.1038/s41598-019-48484-8 |
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