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Mitochondrial 2,4-dienoyl-CoA reductase (Decr) deficiency and impairment of thermogenesis in mouse brown adipose tissue

A large number of studies have demonstrated significance of polyunsaturated fatty acids (PUFAs) for human health. However, many aspects on signals translating PUFA-sensing into body homeostasis have remained enigmatic. To shed light on PUFA physiology, we have generated a mouse line defective in mit...

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Detalles Bibliográficos
Autores principales: Mäkelä, Anne M., Hohtola, Esa, Miinalainen, Ilkka J., Autio, Joonas A., Schmitz, Werner, Niemi, Kalle J., Hiltunen, J. Kalervo, Autio, Kaija J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700156/
https://www.ncbi.nlm.nih.gov/pubmed/31427678
http://dx.doi.org/10.1038/s41598-019-48562-x