Engineered Dendritic Cell-Directed Concurrent Activation of Multiple T cell Inhibitory Pathways Induces Robust Immune Tolerance

Inhibitory/repressor-receptors are upregulated significantly on activated T cells, and have been the molecules of attention as targets for inducing immune tolerance. Induction of effective antigen specific tolerance depends on concurrent engagement of the TCR and one or more of these inhibitory rece...

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Detalles Bibliográficos
Autores principales: Gudi, Radhika R., Karumuthil-Melethil, Subha, Perez, Nicolas, Li, Gongbo, Vasu, Chenthamarakshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700167/
https://www.ncbi.nlm.nih.gov/pubmed/31427630
http://dx.doi.org/10.1038/s41598-019-48464-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700167/
https://www.ncbi.nlm.nih.gov/pubmed/31427630
http://dx.doi.org/10.1038/s41598-019-48464-y

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