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Regulation of gene expression by altered promoter methylation using a CRISPR/Cas9-mediated epigenetic editing system
Despite the increased interest in epigenetic research, its progress has been hampered by a lack of satisfactory tools to control epigenetic factors in specific genomic regions. Until now, many attempts to manipulate DNA methylation have been made using drugs but these drugs are not target-specific a...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700181/ https://www.ncbi.nlm.nih.gov/pubmed/31427598 http://dx.doi.org/10.1038/s41598-019-48130-3 |