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Lack of Neuronal Glycogen Impairs Memory Formation and Learning-Dependent Synaptic Plasticity in Mice

Since brain glycogen is stored mainly in astrocytes, the role of this polysaccharide in neurons has been largely overlooked. To study the existence and relevance of an active neuronal glycogen metabolism in vivo, we generated a mouse model lacking glycogen synthase specifically in the Camk2a-express...

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Detalles Bibliográficos
Autores principales: Duran, Jordi, Gruart, Agnès, Varea, Olga, López-Soldado, Iliana, Delgado-García, José M., Guinovart, Joan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700221/
https://www.ncbi.nlm.nih.gov/pubmed/31456667
http://dx.doi.org/10.3389/fncel.2019.00374