Neonatal T Follicular Helper Cells Are Lodged in a Pre-T Follicular Helper Stage Favoring Innate Over Adaptive Germinal Center Responses

T follicular helper (T(fh)) cells have emerged as a critical limiting factor for controlling the magnitude of neonatal germinal center (GC) reactions and primary vaccine antibody responses. We compared the functional attributes of neonatal and adult T(fh) cells at the transcriptomic level and demons...

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Detalles Bibliográficos
Autores principales: Mastelic-Gavillet, Beatris, Vono, Maria, Gonzalez-Dias, Patrícia, Ferreira, Frederico Moraes, Cardozo, Lucas, Lambert, Paul-Henri, Nakaya, Helder I., Siegrist, Claire-Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700230/
https://www.ncbi.nlm.nih.gov/pubmed/31456798
http://dx.doi.org/10.3389/fimmu.2019.01845

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