Mass Production of Highly Active NK Cells for Cancer Immunotherapy in a GMP Conform Perfusion Bioreactor

NK cells have emerged as promising candidates for cancer immunotherapy, especially due to their ability to fight circulating tumor cells thereby preventing metastases formation. Hence several studies have been performed to generate and expand highly cytotoxic NK cells ex vivo, e.g., by using specifi...

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Detalles Bibliográficos
Autores principales: Bröker, Katharina, Sinelnikov, Evgeny, Gustavus, Dirk, Schumacher, Udo, Pörtner, Ralf, Hoffmeister, Hans, Lüth, Stefan, Dammermann, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700243/
https://www.ncbi.nlm.nih.gov/pubmed/31457007
http://dx.doi.org/10.3389/fbioe.2019.00194

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