Cargando…

OSM-induced CD44 contributes to breast cancer metastatic potential through cell detachment but not epithelial-mesenchymal transition

BACKGROUND: Hormone receptor status in human breast cancer cells is a strong indicator of the aggressiveness of a tumor. Triple negative breast cancers (TNBC) are aggressive, difficult to treat, and contribute to high incidences of metastasis by possessing characteristics such as increased tumor cel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Covert, Hunter, Mellor, Liliana F, Wolf, Cody L, Ankenbrandt, Nicole, Emathinger, Jacqueline M, Tawara, Ken, Oxford, Julie Thom, Jorcyk, Cheryl L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700398/ https://www.ncbi.nlm.nih.gov/pubmed/31496817 http://dx.doi.org/10.2147/CMAR.S208721

Ejemplares similares

HIGH expression of OSM and IL-6 are associated with decreased breast cancer survival: synergistic induction of IL-6 secretion by OSM and IL-1β
por: Tawara, Ken, et al.
Publicado: (2019)

The Effect of OSM on MC3T3-E1 Osteoblastic Cells in Simulated Microgravity with Radiation
por: Goyden, Jake, et al.
Publicado: (2015)

OSM potentiates preintravasation events, increases CTC counts, and promotes breast cancer metastasis to the lung
por: Tawara, Ken, et al.
Publicado: (2018)

The clinical relevance of OSM in inflammatory diseases: a comprehensive review
por: Wolf, Cody L., et al.
Publicado: (2023)

Stüve-Wiedemann syndrome: LIFR and associated cytokines in clinical course and etiology
por: Mikelonis, Dawn, et al.
Publicado: (2014)

Endoplasmic Reticulum Stress and Unfolded Protein Response in Cartilage Pathophysiology; Contributing Factors to Apoptosis and Osteoarthritis
por: Hughes, Alexandria, et al.
Publicado: (2017)

Clinical significance of interleukin (IL)-6 in cancer metastasis to bone: potential of anti-IL-6 therapies
por: Tawara, Ken, et al.
Publicado: (2011)

Emerging Perspectives on Leukemia Inhibitory Factor and its Receptor in Cancer
por: Christianson, Joe, et al.
Publicado: (2021)

Novel mechanism for OSM-promoted extracellular matrix remodeling in breast cancer: LOXL2 upregulation and subsequent ECM alignment
por: Dinca, Simion C., et al.
Publicado: (2021)

DICER1 Syndrome: DICER1 Mutations in Rare Cancers
por: Robertson, Jake C., et al.
Publicado: (2018)

Co-Expression of VEGF and IL-6 Family Cytokines is Associated with Decreased Survival in HER2 Negative Breast Cancer Patients: Subtype-Specific IL-6 Family Cytokine-Mediated VEGF Secretion()()
por: Tawara, Ken, et al.
Publicado: (2018)

Novel mouse mammary cell lines for in vivo bioluminescence imaging (BLI) of bone metastasis
por: Bolin, Celeste, et al.
Publicado: (2012)

IL-6 and ovarian cancer: inflammatory cytokines in promotion of metastasis
por: Browning, Landon, et al.
Publicado: (2018)

Functional Analysis of OsMED16 and OsMED25 in Response to Biotic and Abiotic Stresses in Rice
por: Zhang, Huijuan, et al.
Publicado: (2021)

Extracellular proteins OSM-7 and OSM-8 are required for stress response gene regulation at all post-embryonic stages
por: Rodriguez Mendoza, Victoria, et al.
Publicado: (2022)

Concomitant Activation of OSM and LIF Receptor by a Dual-Specific hlOSM Variant Confers Cardioprotection after Myocardial Infarction in Mice
por: Lörchner, Holger, et al.
Publicado: (2021)

ImOSM: Intermittent Evolution and Robustness of Phylogenetic Methods
por: Thi Nguyen, Minh Anh, et al.
Publicado: (2012)

External tape readers: Integration into CTA and OSM/Enstore cases
por: Camarero Vera, Jorge
Publicado: (2023)

Using Crowdsourced Trajectories for Automated OSM Data Entry Approach
por: Basiri, Anahid, et al.
Publicado: (2016)

Identification of RAGE and OSM as New Prognosis Biomarkers of Severe Pneumonia
por: Lei, Jing, et al.
Publicado: (2022)

OSM-SLAM: Aiding SLAM with OpenStreetMaps priors
por: Frosi, Matteo, et al.
Publicado: (2023)

OSM Enhances Angiogenesis and Improves Cardiac Function after Myocardial Infarction
por: Zhang, Xiaotian, et al.
Publicado: (2015)

Characterisation of a New Family of Carboxyl Esterases with an OsmC Domain
por: Jensen, Mai-Britt V., et al.
Publicado: (2016)

OSM/OSMR and Interleukin 6 Family Cytokines in Physiological and Pathological Condition
por: Lantieri, Francesca, et al.
Publicado: (2022)

REPURPOSING OF FDA APPROVED COMPOUNDS TO INHIBIT OSM/OSMR SIGNALING IN GLIOBLASTOMA
por: Lotfipour, Farzaneh, et al.
Publicado: (2023)

Autoinhibition regulates the motility of the C. elegans intraflagellar transport motor OSM-3
por: Imanishi, Miki, et al.
Publicado: (2006)

Identification and analysis of urban functional area in Hangzhou based on OSM and POI data
por: Wang, Ziyi, et al.
Publicado: (2021)

Nullomer peptide increases immune cell infiltration and reduces tumor metabolism in triple negative breast cancer mouse model
por: Ali, Nilufar, et al.
Publicado: (2023)

Argentine ant extract induces an osm-9 dependent chemotaxis response in C. elegans
por: Alfonso, Sebastian A., et al.
Publicado: (2023)

CHANGES IN LEVELS OF SUBSTRATES AND ENZYMES IN OSME ORGANS OF FEMALE RATS IN RESPONSE TO PLANT EXTRACT
por: Krishna Reddy, M., et al.
Publicado: (1991)

Anti-OSM Antibody Inhibits Tubulointerstitial Lesion in a Murine Model of Lupus Nephritis
por: Liu, Qingjuan, et al.
Publicado: (2017)

OsMS188 Is a Key Regulator of Tapetum Development and Sporopollenin Synthesis in Rice
por: Han, Yu, et al.
Publicado: (2021)

Overexpression of OsMed16 Inhibits the Growth of Rice and Causes Spontaneous Cell Death
por: Jiang, Jie, et al.
Publicado: (2021)

Heterocellular OSM-OSMR signalling reprograms fibroblasts to promote pancreatic cancer growth and metastasis
por: Lee, Brian Y., et al.
Publicado: (2021)

OSM-11 Facilitates LIN-12 Notch Signaling during Caenorhabditis elegans Vulval Development
por: Komatsu, Hidetoshi, et al.
Publicado: (2008)

Nicotinamide is an endogenous agonist for a C. elegans TRPV OSM-9 and OCR-4 channel
por: Upadhyay, Awani, et al.
Publicado: (2016)

Activation of OSM-STAT3 Epigenetically Regulates Tumor-Promoting Transcriptional Programs in Cervical Cancer
por: Noh, Junho, et al.
Publicado: (2022)

The role of the oncostatin M/OSM receptor β axis in activating dermal microvascular endothelial cells in systemic sclerosis
por: Marden, G., et al.
Publicado: (2020)

A General Framework for 3-D Parameters Estimation of Roads Using GPS, OSM and DEM Data
por: Boucher, Christophe, et al.
Publicado: (2017)

OSM-9 and OCR-2 TRPV channels are accessorial warm receptors in Caenorhabditis elegans temperature acclimatisation
por: Ohnishi, Kohei, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_m79eht3busoh1chq78aj468esu