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Visualizing modules of coordinated structural brain atrophy during the course of conversion to Alzheimer's disease by applying methodology from gene co-expression analysis

OBJECTIVE: We aimed to identify modularized structural atrophy of brain regions with a high degree of connectivity and its longitudinal changes associated with the progression of Alzheimer's disease (AD) using weighted gene co-expression network analysis (WGCNA), which is an unsupervised hierar...

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Detalles Bibliográficos
Autores principales: Sato, Kenichiro, Mano, Tatsuo, Matsuda, Hiroshi, Senda, Michio, Ihara, Ryoko, Suzuki, Kazushi, Arai, Hiroyuki, Ishii, Kenji, Ito, Kengo, Ikeuchi, Takeshi, Kuwano, Ryozo, Toda, Tatsushi, Iwatsubo, Takeshi, Iwata, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700430/
https://www.ncbi.nlm.nih.gov/pubmed/31400633
http://dx.doi.org/10.1016/j.nicl.2019.101957