Phenotype-Based High-Throughput Classification of Long QT Syndrome Subtypes Using Human Induced Pluripotent Stem Cells

For long QT syndrome (LQTS), recent progress in genome-sequencing technologies enabled the identification of rare genomic variants with diagnostic, prognostic, and therapeutic implications. However, pathogenic stratification of the identified variants remains challenging, especially in variants of u...

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Detalles Bibliográficos
Autores principales: Yoshinaga, Daisuke, Baba, Shiro, Makiyama, Takeru, Shibata, Hirofumi, Hirata, Takuya, Akagi, Kentaro, Matsuda, Koichi, Kohjitani, Hirohiko, Wuriyanghai, Yimin, Umeda, Katsutsugu, Yamamoto, Yuta, Conklin, Bruce R., Horie, Minoru, Takita, Junko, Heike, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700479/
https://www.ncbi.nlm.nih.gov/pubmed/31378668
http://dx.doi.org/10.1016/j.stemcr.2019.06.007

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