Dual CTLA-4 and PD-L1 Blockade Inhibits Tumor Growth and Liver Metastasis in a Highly Aggressive Orthotopic Mouse Model of Colon Cancer()()

Immune checkpoint inhibitors have shown clinical benefit in several cancer entities including metastatic microsatellite instable colorectal carcinomas. However, for the majority of metastatic colorectal carcinomas the potential and limitations of immune checkpoint inhibition is not fully understood....

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Detalles Bibliográficos
Autores principales: Fiegle, E, Doleschel, D, Koletnik, S, Rix, A, Weiskirchen, R, Borkham-Kamphorst, E, Kiessling, F, Lederle, W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2019
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700499/
https://www.ncbi.nlm.nih.gov/pubmed/31412307
http://dx.doi.org/10.1016/j.neo.2019.07.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700499/
https://www.ncbi.nlm.nih.gov/pubmed/31412307
http://dx.doi.org/10.1016/j.neo.2019.07.006

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