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Group B streptococcus meningitis complicated by periodic lateralising epileptiform discharges in an elderly patient with type 2 diabetes mellitus
Streptococcus agalactiae (group B streptococcus or GBS) is the most common cause of bacterial meningitis in infants, but is rarely the cause in adults. Across all non-pregnant adults it comprises 7% of bacterial meningitis cases, with a mortality rate of 56% in the elderly. Therefore, while rare, GB...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700676/ https://www.ncbi.nlm.nih.gov/pubmed/31399414 http://dx.doi.org/10.1136/bcr-2018-228040 |
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author | Germano, Nicholas Sibbel, Maria Gunnes Summerfield, Douglas Pitzenberger, Abbey |
author_facet | Germano, Nicholas Sibbel, Maria Gunnes Summerfield, Douglas Pitzenberger, Abbey |
author_sort | Germano, Nicholas |
collection | PubMed |
description | Streptococcus agalactiae (group B streptococcus or GBS) is the most common cause of bacterial meningitis in infants, but is rarely the cause in adults. Across all non-pregnant adults it comprises 7% of bacterial meningitis cases, with a mortality rate of 56% in the elderly. Therefore, while rare, GBS should be a part of a patient’s differential when initiating antibiotics in adults with chronic illnesses. We report a 78-year-old diabetic female admitted to the hospital with suspected meningitis. Lumbar puncture revealed grossly purulent cerebrospinal fluid (CSF) and she was started on antibiotics for empiric treatment of expected Streptococcus pneumoniae. Thirty-one hours post-sampling, the CSF culture results returned positive for beta haemolytic GBS and treatment was altered accordingly. The case was complicated by concomitant periodic lateralising epileptiform discharges which were treated simultaneously. After 14 days of hospitalisation, the patient was discharged to a skilled nursing facility for further recovery. |
format | Online Article Text |
id | pubmed-6700676 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-67006762019-08-29 Group B streptococcus meningitis complicated by periodic lateralising epileptiform discharges in an elderly patient with type 2 diabetes mellitus Germano, Nicholas Sibbel, Maria Gunnes Summerfield, Douglas Pitzenberger, Abbey BMJ Case Rep Reminder of Important Clinical Lesson Streptococcus agalactiae (group B streptococcus or GBS) is the most common cause of bacterial meningitis in infants, but is rarely the cause in adults. Across all non-pregnant adults it comprises 7% of bacterial meningitis cases, with a mortality rate of 56% in the elderly. Therefore, while rare, GBS should be a part of a patient’s differential when initiating antibiotics in adults with chronic illnesses. We report a 78-year-old diabetic female admitted to the hospital with suspected meningitis. Lumbar puncture revealed grossly purulent cerebrospinal fluid (CSF) and she was started on antibiotics for empiric treatment of expected Streptococcus pneumoniae. Thirty-one hours post-sampling, the CSF culture results returned positive for beta haemolytic GBS and treatment was altered accordingly. The case was complicated by concomitant periodic lateralising epileptiform discharges which were treated simultaneously. After 14 days of hospitalisation, the patient was discharged to a skilled nursing facility for further recovery. BMJ Publishing Group 2019-08-08 /pmc/articles/PMC6700676/ /pubmed/31399414 http://dx.doi.org/10.1136/bcr-2018-228040 Text en © BMJ Publishing Group Limited 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
spellingShingle | Reminder of Important Clinical Lesson Germano, Nicholas Sibbel, Maria Gunnes Summerfield, Douglas Pitzenberger, Abbey Group B streptococcus meningitis complicated by periodic lateralising epileptiform discharges in an elderly patient with type 2 diabetes mellitus |
title | Group B streptococcus meningitis complicated by periodic lateralising epileptiform discharges in an elderly patient with type 2 diabetes mellitus |
title_full | Group B streptococcus meningitis complicated by periodic lateralising epileptiform discharges in an elderly patient with type 2 diabetes mellitus |
title_fullStr | Group B streptococcus meningitis complicated by periodic lateralising epileptiform discharges in an elderly patient with type 2 diabetes mellitus |
title_full_unstemmed | Group B streptococcus meningitis complicated by periodic lateralising epileptiform discharges in an elderly patient with type 2 diabetes mellitus |
title_short | Group B streptococcus meningitis complicated by periodic lateralising epileptiform discharges in an elderly patient with type 2 diabetes mellitus |
title_sort | group b streptococcus meningitis complicated by periodic lateralising epileptiform discharges in an elderly patient with type 2 diabetes mellitus |
topic | Reminder of Important Clinical Lesson |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700676/ https://www.ncbi.nlm.nih.gov/pubmed/31399414 http://dx.doi.org/10.1136/bcr-2018-228040 |
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