Folding Then Binding vs Folding Through Binding in Macrocyclic Peptide Inhibitors of Human Pancreatic α-Amylase

[Image: see text] De novo macrocyclic peptides, derived using selection technologies such as phage and mRNA display, present unique and unexpected solutions to challenging biological problems. This is due in part to their unusual folds, which are able to present side chains in ways not available to...

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Detalles Bibliográficos
Autores principales: Goldbach, Leander, Vermeulen, Bram J. A., Caner, Sami, Liu, Minglong, Tysoe, Christina, van Gijzel, Lieke, Yoshisada, Ryoji, Trellet, Mikael, van Ingen, Hugo, Brayer, Gary D., Bonvin, Alexandre M. J. J., Jongkees, Seino A. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700688/
https://www.ncbi.nlm.nih.gov/pubmed/31241898
http://dx.doi.org/10.1021/acschembio.9b00290

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