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Intestinal enteroids/organoids: A novel platform for drug discovery in inflammatory bowel diseases
The introduction of biologics such as anti-tumor necrosis factor (TNF) monoclonal antibodies followed by anti-integrins has dramatically changed the therapeutic paradigm of inflammatory bowel diseases (IBD). Furthermore, a newly developed anti-p40 subunit of interleukin (IL)-12 and IL-23 (ustekinuma...
Autores principales: | Yoo, Jun-Hwan, Donowitz, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700704/ https://www.ncbi.nlm.nih.gov/pubmed/31435168 http://dx.doi.org/10.3748/wjg.v25.i30.4125 |
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