Transcriptome profiling of brain myeloid cells revealed activation of Itgal, Trem1, and Spp1 in western diet-induced obesity

BACKGROUND: Environmental factors are critical in the development of age-related cognitive decline and dementia. A western diet (WD) can cause nutrient deficiency and inflammation that could impact cognition directly. It is increasingly recognized that innate immune responses by brain myeloid cells,...

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Detalles Bibliográficos
Autores principales: Yang, Hongtian, Graham, Leah C., Reagan, Alaina M., Grabowska, Weronika A., Schott, William H., Howell, Gareth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700800/
https://www.ncbi.nlm.nih.gov/pubmed/31426806
http://dx.doi.org/10.1186/s12974-019-1527-z

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