Caffeic acid phenethyl ester suppresses androgen receptor signaling and stability via inhibition of phosphorylation on Ser81 and Ser213

BACKGROUND: Androgen receptor (AR) plays important role in the development, progression, and metastasis of prostate cancer (PCa). Caffeic acid phenethyl ester (CAPE) is the main component of honey bee propolis. We determined if CAPE affects the signaling and stability of AR in PCa cells. METHODS: Ef...

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Detalles Bibliográficos
Autores principales: Kuo, Ying-Yu, Huo, Chieh, Lin, Ching-Yu, Lin, Hui-Ping, Liu, Jai-Shin, Wang, Wen-Ching, Chang, Chuang-Rung, Chuu, Chih-Pin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700801/
https://www.ncbi.nlm.nih.gov/pubmed/31429764
http://dx.doi.org/10.1186/s12964-019-0404-9

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