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Compartmentalization of anti-oxidant and anti-inflammatory gene expression in current and former smokers with COPD
BACKGROUND: Patients with chronic obstructive pulmonary disease (COPD) have high oxidative stress associated with the severity of the disease. Nuclear factor erythroid-2 related factor 2 (Nrf2)-directed stress response plays a critical role in the protection of lung cells to oxidative stress by upre...
Autores principales: | Sidhaye, Venkataramana K., Holbrook, Janet T., Burke, Alyce, Sudini, Kuladeep R., Sethi, Sanjay, Criner, Gerard J., Fahey, Jed W., Berenson, Charles S., Jacobs, Michael R., Thimmulappa, Rajesh, Wise, Robert A., Biswal, Shyam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700818/ https://www.ncbi.nlm.nih.gov/pubmed/31429757 http://dx.doi.org/10.1186/s12931-019-1164-1 |
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