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Primary glaucoma surgery in Fuchs’ heterochromic uveitis: a comparison of trabeculectomy versus deep sclerectomy
BACKGROUND: Deep sclerectomy offers the potential advantage of less postoperative inflammation and better survival in Fuchs’ patients. The aim of this study was to compare survival and safety profiles of Fuchs’ heterochromic uveitis patients undergoing trabeculectomy or deep sclerectomy. METHODS: A...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700865/ https://www.ncbi.nlm.nih.gov/pubmed/31453432 http://dx.doi.org/10.1177/2515841419869761 |
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author | Walkden, Andrew Mercieca, Karl Perumal, Divya Anand, Nitin |
author_facet | Walkden, Andrew Mercieca, Karl Perumal, Divya Anand, Nitin |
author_sort | Walkden, Andrew |
collection | PubMed |
description | BACKGROUND: Deep sclerectomy offers the potential advantage of less postoperative inflammation and better survival in Fuchs’ patients. The aim of this study was to compare survival and safety profiles of Fuchs’ heterochromic uveitis patients undergoing trabeculectomy or deep sclerectomy. METHODS: A retrospective study was conducted of two separate cohorts who had undergone either trabeculectomy or deep sclerectomy. Patient demographics, best-corrected visual acuity, intraocular pressure, antimetabolite used, postoperative complications and subsequent procedures were analysed. RESULTS: In total, 13 trabeculectomy patients and 14 deep sclerectomy patients were included. Mean preoperative intraocular pressure was similar at 30.1 mmHg in the trabeculectomy group and 35.9 mmHg in the deep sclerectomy group, with no significant difference between the two (p = 0.22). Kaplan–Meier survival outcomes for success at <22 mmHg and <19 mmHg showed no significant differences between the groups and this was also the case for intraocular pressure at 3 years (analysis of variance; p = 0.47). CONCLUSION: Both procedures appear to have similar efficacy and safety profiles, suggesting that both are effective. |
format | Online Article Text |
id | pubmed-6700865 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-67008652019-08-26 Primary glaucoma surgery in Fuchs’ heterochromic uveitis: a comparison of trabeculectomy versus deep sclerectomy Walkden, Andrew Mercieca, Karl Perumal, Divya Anand, Nitin Ther Adv Ophthalmol Original Research BACKGROUND: Deep sclerectomy offers the potential advantage of less postoperative inflammation and better survival in Fuchs’ patients. The aim of this study was to compare survival and safety profiles of Fuchs’ heterochromic uveitis patients undergoing trabeculectomy or deep sclerectomy. METHODS: A retrospective study was conducted of two separate cohorts who had undergone either trabeculectomy or deep sclerectomy. Patient demographics, best-corrected visual acuity, intraocular pressure, antimetabolite used, postoperative complications and subsequent procedures were analysed. RESULTS: In total, 13 trabeculectomy patients and 14 deep sclerectomy patients were included. Mean preoperative intraocular pressure was similar at 30.1 mmHg in the trabeculectomy group and 35.9 mmHg in the deep sclerectomy group, with no significant difference between the two (p = 0.22). Kaplan–Meier survival outcomes for success at <22 mmHg and <19 mmHg showed no significant differences between the groups and this was also the case for intraocular pressure at 3 years (analysis of variance; p = 0.47). CONCLUSION: Both procedures appear to have similar efficacy and safety profiles, suggesting that both are effective. SAGE Publications 2019-08-19 /pmc/articles/PMC6700865/ /pubmed/31453432 http://dx.doi.org/10.1177/2515841419869761 Text en © The Author(s), 2019 http://www.creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Research Walkden, Andrew Mercieca, Karl Perumal, Divya Anand, Nitin Primary glaucoma surgery in Fuchs’ heterochromic uveitis: a comparison of trabeculectomy versus deep sclerectomy |
title | Primary glaucoma surgery in Fuchs’ heterochromic uveitis: a comparison of trabeculectomy versus deep sclerectomy |
title_full | Primary glaucoma surgery in Fuchs’ heterochromic uveitis: a comparison of trabeculectomy versus deep sclerectomy |
title_fullStr | Primary glaucoma surgery in Fuchs’ heterochromic uveitis: a comparison of trabeculectomy versus deep sclerectomy |
title_full_unstemmed | Primary glaucoma surgery in Fuchs’ heterochromic uveitis: a comparison of trabeculectomy versus deep sclerectomy |
title_short | Primary glaucoma surgery in Fuchs’ heterochromic uveitis: a comparison of trabeculectomy versus deep sclerectomy |
title_sort | primary glaucoma surgery in fuchs’ heterochromic uveitis: a comparison of trabeculectomy versus deep sclerectomy |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6700865/ https://www.ncbi.nlm.nih.gov/pubmed/31453432 http://dx.doi.org/10.1177/2515841419869761 |
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