Targeting metastatic breast cancer with peptide epitopes derived from autocatalytic loop of Prss14/ST14 membrane serine protease and with monoclonal antibodies

BACKGROUND: In order to develop a new immunotherapeutic agent targeting metastatic breast cancers, we chose to utilize autocatalytic feature of the membrane serine protease Prss14/ST14, a specific prognosis marker for ER negative breast cancer as a target molecule. METHODS: The study was conducted u...

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Detalles Bibliográficos
Autores principales: Kim, Ki Yeon, Yoon, Minsang, Cho, Youngkyung, Lee, Kwang-Hoon, Park, Sora, Lee, Se-ra, Choi, So-Young, Lee, Deokjae, Yang, Chansik, Cho, Eun Hye, Jeon, Sangjun Davie, Kim, Seok-Hyung, Kim, Chungho, Kim, Moon Gyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701106/
https://www.ncbi.nlm.nih.gov/pubmed/31426843
http://dx.doi.org/10.1186/s13046-019-1373-y

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