Cargando…

Astragaloside III Enhances Anti-Tumor Response of NK Cells by Elevating NKG2D and IFN-γ

Natural killer (NK) cells play an irreplaceable role in the development of colon cancer, in which antitumor function of NK cells was impaired. Astragaloside III is a natural compound from Astragalus that has been shown to have immunomodulatory effects in various systems. However, few studies have ev...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Xingmeng, Chen, Xi, Gao, Junxiao, Yang, Han, Duan, Yue, Feng, Yuxin, He, Xin, Gong, Xiaoqun, Wang, Hanjie, Wu, Xiaoli, Chang, Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701288/ https://www.ncbi.nlm.nih.gov/pubmed/31456687 http://dx.doi.org/10.3389/fphar.2019.00898

Ejemplares similares

Activated NK cells reprogram MDSCs via NKG2D-NKG2DL and IFN-γ to modulate antitumor T-cell response after cryo-thermal therapy
por: Peng, Peng, et al.
Publicado: (2022)

Suppressing NK Cells by Astragaloside IV Protects Against Acute Ischemic Stroke in Mice Via Inhibiting STAT3
por: Li, Shichun, et al.
Publicado: (2022)

NKG2D(+) IFN-γ(+) CD8(+) T Cells Are Responsible for Palladium Allergy
por: Kawano, Mitsuko, et al.
Publicado: (2014)

Astragaloside IV, as a potential anticancer agent
por: Xia, Dongqin, et al.
Publicado: (2023)

Tonsillar CD56brightNKG2A+ NK cells restrict primary Epstein-Barr virus infection in B cells via IFN-γ
por: Jud, Aurelia, et al.
Publicado: (2016)

IFN-γ modulates Ly-49 receptors on NK cells in IFN-γ-induced pregnancy failure
por: Li, Zhong-Yin, et al.
Publicado: (2015)

Review on the protective mechanism of astragaloside IV against cardiovascular diseases
por: Yang, Chunkun, et al.
Publicado: (2023)

IFN type III: in vivo NK cell response
por: Souza-Fonseca-Guimaraes, Fernando, et al.
Publicado: (2015)

Lipopolysaccharide induces IFN-γ production in human NK cells
por: Kanevskiy, Leonid M., et al.
Publicado: (2013)

CD160 is essential for NK-mediated IFN-γ production
por: Tu, Tony C., et al.
Publicado: (2015)

Neuroprotective Effect of Astragaloside IV on Cerebral Ischemia/Reperfusion Injury Rats Through Sirt1/Mapt Pathway
por: Shi, Yi-Hua, et al.
Publicado: (2021)

IFN-γ-dependent NK cell activation is essential to metastasis suppression by engineered Salmonella
por: Lin, Qiubin, et al.
Publicado: (2021)

Astragaloside IV Attenuates the Myocardial Injury Caused by Adriamycin by Inhibiting Autophagy
por: Luo, Li-Fei, et al.
Publicado: (2021)

The Mechanism Actions of Astragaloside IV Prevents the Progression of Hypertensive Heart Disease Based on Network Pharmacology and Experimental Pharmacology
por: Jing, Haoran, et al.
Publicado: (2021)

Elevated serum IFN-γand IFN-γ/IL-6 ratio in Kikuchi-Fujimoto disease
por: He, Tingyan, et al.
Publicado: (2023)

Therapeutic Potential of Astragaloside IV Against Adriamycin-Induced Renal Damage in Rats via Ferroptosis
por: Qin, Lu-Yun, et al.
Publicado: (2022)

Subchronic Oral Toxicity of Sodium p-Hydroxybenzoate in Sprague-Dawley Rats
por: Fan, Xiaoli, et al.
Publicado: (2022)

Elucidation of the binding mechanism of astragaloside IV derivative with human serum albumin and its cardiotoxicity in zebrafish embryos
por: Wu, You-Jiao, et al.
Publicado: (2022)

Astragaloside IV attenuates ferroptosis after subarachnoid hemorrhage via Nrf2/HO-1 signaling pathway
por: Liu, Zhuanghua, et al.
Publicado: (2022)

Astragaloside II Ameliorated Podocyte Injury and Mitochondrial Dysfunction in Streptozotocin-Induced Diabetic Rats
por: Su, Jun, et al.
Publicado: (2021)

Calcium Sensing Receptor-Related Pathway Contributes to Cardiac Injury and the Mechanism of Astragaloside IV on Cardioprotection
por: Lu, Meili, et al.
Publicado: (2018)

Astragaloside IV Improves Bleomycin-Induced Pulmonary Fibrosis in Rats by Attenuating Extracellular Matrix Deposition
por: Li, Liu-Cheng, et al.
Publicado: (2017)

NKG2C+ NK Cells for Immunotherapy of Glioblastoma Multiforme
por: Murad, Shafiq, et al.
Publicado: (2022)

NKG2A is a NK cell exhaustion checkpoint for HCV persistence
por: Zhang, Chao, et al.
Publicado: (2019)

The NK cell checkpoint NKG2A maintains expansion capacity of human NK cells
por: Kaulfuss, Meike, et al.
Publicado: (2023)

The Effect of Astragaloside on Pacemaker Current and the Cytoskeleton in Rabbit Sinoatrial Node Cells Under the Ischemia and Reperfusion Condition
por: Liu, Ruxiu, et al.
Publicado: (2018)

Astragaloside IV improves the pharmacokinetics of febuxostat in rats with hyperuricemic nephropathy by regulating urea metabolism in gut microbiota
por: Zhao, Zhen Xiong, et al.
Publicado: (2022)

Potential of the NKG2D/NKG2DL Axis in NK Cell-Mediated Clearance of the HIV-1 Reservoir
por: Desimio, Maria G., et al.
Publicado: (2019)

Phenotypic and Functional Analysis of Human NK Cell Subpopulations According to the Expression of FcεRIγ and NKG2C
por: Kim, Kyung Hwan, et al.
Publicado: (2019)

Genome-Wide CRISPR Screen Reveals Cancer Cell Resistance to NK Cells Induced by NK-Derived IFN-γ
por: Zhuang, Xiaoxuan, et al.
Publicado: (2019)

Fufang shenhua tablet, astragali radix and its active component astragaloside IV: Research progress on anti-inflammatory and immunomodulatory mechanisms in the kidney
por: Li, Run, et al.
Publicado: (2023)

Astragaloside IV promotes pharmacological effect of Descurainia sophia seeds on isoproterenol-induced cardiomyopathy in rats by synergistically modulating the myosin motor
por: Liu, Xingkai, et al.
Publicado: (2022)

Astragaloside IV Exerts Cognitive Benefits and Promotes Hippocampal Neurogenesis in Stroke Mice by Downregulating Interleukin-17 Expression via Wnt Pathway
por: Sun, Li, et al.
Publicado: (2020)

Astragaloside IV Attenuated 3,4-Benzopyrene-Induced Abdominal Aortic Aneurysm by Ameliorating Macrophage-Mediated Inflammation
por: Wang, Jiaoni, et al.
Publicado: (2018)

Astragaloside IV Exerts Cardioprotection in Animal Models of Viral Myocarditis: A Preclinical Systematic Review and Meta-Analysis
por: Zhuang, Zhuang, et al.
Publicado: (2019)

A Mechanistic Exploratory Study on the Therapeutic Efficacy of Astragaloside IV Against Diabetic Retinopathy Revealed by Network Pharmacology
por: Zhao, Zhi-Hao, et al.
Publicado: (2022)

Astragaloside IV Derivative (LS-102) Alleviated Myocardial Ischemia Reperfusion Injury by Inhibiting Drp1(Ser616) Phosphorylation-Mediated Mitochondrial Fission
por: Chen, Li, et al.
Publicado: (2020)

Inhibitory NKG2A(+) and absent activating NKG2C(+) NK cell responses are associated with the development of EBV(+) lymphomas
por: Vietzen, Hannes, et al.
Publicado: (2023)

Astragaloside IV alleviates 1-deoxysphinganine-induced mitochondrial dysfunction during the progression of chronic kidney disease through p62-Nrf2 antioxidant pathway
por: Gui, Ting, et al.
Publicado: (2023)

Identification of Hub Genes in Protective Effect of Astragaloside IV on Aconitine-Induced Cardiac Damage in Zebrafish Based on Bioinformatics Analysis
por: Wang, Mingzhu, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_dofq1q6diaie5sn42rvjpba1ta