Primary Tumor Site Specificity is Preserved in Patient-Derived Tumor Xenograft Models

Patient-derived tumor xenograft (PDX) mouse models are widely used for drug screening. The underlying assumption is that PDX tissue is very similar with the original patient tissue, and it has the same response to the drug treatment. To investigate whether the primary tumor site information is well...

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Detalles Bibliográficos
Autores principales: Chen, Lei, Pan, Xiaoyong, Zhang, Yu-Hang, Hu, Xiaohua, Feng, KaiYan, Huang, Tao, Cai, Yu-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701289/
https://www.ncbi.nlm.nih.gov/pubmed/31456818
http://dx.doi.org/10.3389/fgene.2019.00738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701289/
https://www.ncbi.nlm.nih.gov/pubmed/31456818
http://dx.doi.org/10.3389/fgene.2019.00738

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