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The Analysis of In Vivo Aging in Human Bone Marrow Mesenchymal Stromal Cells Using Colony-Forming Unit-Fibroblast Assay and the CD45(low)CD271(+) Phenotype
Uncultured mesenchymal stromal cells (MSCs) are increasingly used in therapies; however, the effects of donor age on their biological characteristics and gene expression remain unclear. The aim of this study was to investigate age-related changes in bone marrow (BM) MSCs following minimal or no cult...
Autores principales: | Ganguly, Payal, El-Jawhari, Jehan J., Burska, Agata N., Ponchel, Frederique, Giannoudis, Peter V., Jones, Elena A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701348/ https://www.ncbi.nlm.nih.gov/pubmed/31467563 http://dx.doi.org/10.1155/2019/5197983 |
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