A Rare Case of New-Onset Ulcerative Colitis following Initiation of Secukinumab

Secukinumab is an IgG monoclonal antibody widely used for treatment of ankylosing spondylitis, psoriasis, and psoriatic arthritis. Recently, there has been increasing controversy regarding potential adverse effects of the drug especially in those with underlying inflammatory bowel disease. We presen...

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Detalles Bibliográficos
Autores principales: Achufusi, Ted George, Harnee, Prateek S., Rawlins, Sekou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701396/
https://www.ncbi.nlm.nih.gov/pubmed/31467555
http://dx.doi.org/10.1155/2019/2975631
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author Achufusi, Ted George
Harnee, Prateek S.
Rawlins, Sekou
author_facet Achufusi, Ted George
Harnee, Prateek S.
Rawlins, Sekou
author_sort Achufusi, Ted George
collection PubMed
description Secukinumab is an IgG monoclonal antibody widely used for treatment of ankylosing spondylitis, psoriasis, and psoriatic arthritis. Recently, there has been increasing controversy regarding potential adverse effects of the drug especially in those with underlying inflammatory bowel disease. We present the case of a young male patient who developed severe new-onset ulcerative colitis following initiation of secukinumab for psoriasis, with excellent response and rapid resolution of symptoms with infliximab.
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spelling pubmed-67013962019-08-29 A Rare Case of New-Onset Ulcerative Colitis following Initiation of Secukinumab Achufusi, Ted George Harnee, Prateek S. Rawlins, Sekou Case Rep Med Case Report Secukinumab is an IgG monoclonal antibody widely used for treatment of ankylosing spondylitis, psoriasis, and psoriatic arthritis. Recently, there has been increasing controversy regarding potential adverse effects of the drug especially in those with underlying inflammatory bowel disease. We present the case of a young male patient who developed severe new-onset ulcerative colitis following initiation of secukinumab for psoriasis, with excellent response and rapid resolution of symptoms with infliximab. Hindawi 2019-07-31 /pmc/articles/PMC6701396/ /pubmed/31467555 http://dx.doi.org/10.1155/2019/2975631 Text en Copyright © 2019 Ted George Achufusi et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Achufusi, Ted George
Harnee, Prateek S.
Rawlins, Sekou
A Rare Case of New-Onset Ulcerative Colitis following Initiation of Secukinumab
title A Rare Case of New-Onset Ulcerative Colitis following Initiation of Secukinumab
title_full A Rare Case of New-Onset Ulcerative Colitis following Initiation of Secukinumab
title_fullStr A Rare Case of New-Onset Ulcerative Colitis following Initiation of Secukinumab
title_full_unstemmed A Rare Case of New-Onset Ulcerative Colitis following Initiation of Secukinumab
title_short A Rare Case of New-Onset Ulcerative Colitis following Initiation of Secukinumab
title_sort rare case of new-onset ulcerative colitis following initiation of secukinumab
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701396/
https://www.ncbi.nlm.nih.gov/pubmed/31467555
http://dx.doi.org/10.1155/2019/2975631
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