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Modelling the Effect of a Novel Autodissemination Trap on the Spread of Dengue in Shah Alam and Malaysia

In this paper, we will start off by introducing the classical Ross–Macdonald model for vector-borne diseases which we use to describe the transmission of dengue between humans and Aedes mosquitoes in Shah Alam, which is a city and the state capital of Selangor, Malaysia. We will focus on analysing t...

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Autores principales: Liang, Y., Ahmad Mohiddin, M. N., Bahauddin, R., Hidayatul, F. O., Nazni, W. A., Lee, H. L., Greenhalgh, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701433/
https://www.ncbi.nlm.nih.gov/pubmed/31481976
http://dx.doi.org/10.1155/2019/1923479
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author Liang, Y.
Ahmad Mohiddin, M. N.
Bahauddin, R.
Hidayatul, F. O.
Nazni, W. A.
Lee, H. L.
Greenhalgh, D.
author_facet Liang, Y.
Ahmad Mohiddin, M. N.
Bahauddin, R.
Hidayatul, F. O.
Nazni, W. A.
Lee, H. L.
Greenhalgh, D.
author_sort Liang, Y.
collection PubMed
description In this paper, we will start off by introducing the classical Ross–Macdonald model for vector-borne diseases which we use to describe the transmission of dengue between humans and Aedes mosquitoes in Shah Alam, which is a city and the state capital of Selangor, Malaysia. We will focus on analysing the effect of using the Mosquito Home System (MHS), which is an example of an autodissemination trap, in reducing the number of dengue cases by changing the Ross–Macdonald model. By using the national dengue data from Malaysia, we are able to estimate λ, which represents the initial growth rate of the dengue epidemic, and this allows us to estimate the number of mosquitoes in Malaysia. A mathematical expression is also constructed which allows us to estimate the potential number of breeding sites of Aedes mosquitoes. By using the data available from the MHS trial carried out in Section 15 of Shah Alam, we included the potential effect of the MHS into the dengue model and thus modelled the impact MHS has on the spread of dengue within the trial area. We then extended our results to analyse the effect of the MHSs on reducing the number of dengue cases in the whole of Malaysia. A new model was constructed with a basic reproduction number, R (0,Mala) (MHS), which allows us to identify the required MHSs coverage needed to achieve extinction in Malaysia. Numerical simulations and tables of results were also produced to illustrate our results.
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spelling pubmed-67014332019-09-03 Modelling the Effect of a Novel Autodissemination Trap on the Spread of Dengue in Shah Alam and Malaysia Liang, Y. Ahmad Mohiddin, M. N. Bahauddin, R. Hidayatul, F. O. Nazni, W. A. Lee, H. L. Greenhalgh, D. Comput Math Methods Med Research Article In this paper, we will start off by introducing the classical Ross–Macdonald model for vector-borne diseases which we use to describe the transmission of dengue between humans and Aedes mosquitoes in Shah Alam, which is a city and the state capital of Selangor, Malaysia. We will focus on analysing the effect of using the Mosquito Home System (MHS), which is an example of an autodissemination trap, in reducing the number of dengue cases by changing the Ross–Macdonald model. By using the national dengue data from Malaysia, we are able to estimate λ, which represents the initial growth rate of the dengue epidemic, and this allows us to estimate the number of mosquitoes in Malaysia. A mathematical expression is also constructed which allows us to estimate the potential number of breeding sites of Aedes mosquitoes. By using the data available from the MHS trial carried out in Section 15 of Shah Alam, we included the potential effect of the MHS into the dengue model and thus modelled the impact MHS has on the spread of dengue within the trial area. We then extended our results to analyse the effect of the MHSs on reducing the number of dengue cases in the whole of Malaysia. A new model was constructed with a basic reproduction number, R (0,Mala) (MHS), which allows us to identify the required MHSs coverage needed to achieve extinction in Malaysia. Numerical simulations and tables of results were also produced to illustrate our results. Hindawi 2019-08-04 /pmc/articles/PMC6701433/ /pubmed/31481976 http://dx.doi.org/10.1155/2019/1923479 Text en Copyright © 2019 Y. Liang et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Liang, Y.
Ahmad Mohiddin, M. N.
Bahauddin, R.
Hidayatul, F. O.
Nazni, W. A.
Lee, H. L.
Greenhalgh, D.
Modelling the Effect of a Novel Autodissemination Trap on the Spread of Dengue in Shah Alam and Malaysia
title Modelling the Effect of a Novel Autodissemination Trap on the Spread of Dengue in Shah Alam and Malaysia
title_full Modelling the Effect of a Novel Autodissemination Trap on the Spread of Dengue in Shah Alam and Malaysia
title_fullStr Modelling the Effect of a Novel Autodissemination Trap on the Spread of Dengue in Shah Alam and Malaysia
title_full_unstemmed Modelling the Effect of a Novel Autodissemination Trap on the Spread of Dengue in Shah Alam and Malaysia
title_short Modelling the Effect of a Novel Autodissemination Trap on the Spread of Dengue in Shah Alam and Malaysia
title_sort modelling the effect of a novel autodissemination trap on the spread of dengue in shah alam and malaysia
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701433/
https://www.ncbi.nlm.nih.gov/pubmed/31481976
http://dx.doi.org/10.1155/2019/1923479
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