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KAP1 is an antiparallel dimer with a functional asymmetry
KAP1 (KRAB domain–associated protein 1) plays a fundamental role in regulating gene expression in mammalian cells by recruiting different transcription factors and altering the chromatin state. In doing so, KAP1 acts both as a platform for macromolecular interactions and as an E3 small ubiquitin mod...
Autores principales: | Fonti, Giulia, Marcaida, Maria J, Bryan, Louise C, Träger, Sylvain, Kalantzi, Alexandra S, Helleboid, Pierre-Yves JL, Demurtas, Davide, Tully, Mark D, Grudinin, Sergei, Trono, Didier, Fierz, Beat, Dal Peraro, Matteo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701479/ https://www.ncbi.nlm.nih.gov/pubmed/31427381 http://dx.doi.org/10.26508/lsa.201900349 |
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