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Intestinal CD103(+)CD4(+) and CD103(+)CD8(+) T-Cell Subsets in the Gut of Inflammatory Bowel Disease Patients at Diagnosis and During Follow-up
BACKGROUND: The integrin CD103 is proposed to be a potential therapeutical target in inflammatory bowel disease (IBD), as it can form a heterodimeric integrin with β7 (Etrolizumab, anti-β7 integrin) on epithelial T cells. Therefore, we aimed to study the frequencies of different intestinal CD103(+)T...
Autores principales: | Roosenboom, Britt, Wahab, Peter J, Smids, Carolijn, Groenen, Marcel J M, van Koolwijk, Elly, van Lochem, Ellen G, Horjus Talabur Horje, Carmen S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701511/ https://www.ncbi.nlm.nih.gov/pubmed/30918941 http://dx.doi.org/10.1093/ibd/izz049 |
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