Cargando…

TCF1 and LEF1 Control Treg Competitive Survival and Tfr Development to Prevent Autoimmune Diseases

CD4(+) Foxp3(+) T regulatory (Treg) cells are key players in preventing lethal autoimmunity. Tregs undertake differentiation processes and acquire diverse functional properties. However, how Treg’s differentiation and functional specification are regulated remains incompletely understood. Here, we r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Bi-Huei, Wang, Ke, Wan, Shuo, Liang, Yan, Yuan, Xiaomei, Dong, Yi, Cho, Sunglim, Xu, Wanqing, Jepsen, Kristen, Feng, Gen-Sheng, Lu, Li-Fan, Xue, Hai-Hui, Fu, Wenxian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701704/ https://www.ncbi.nlm.nih.gov/pubmed/31216480 http://dx.doi.org/10.1016/j.celrep.2019.05.061

Ejemplares similares

Tcf1 and Lef1 are required for the immunosuppressive function of regulatory T cells
por: Xing, Shaojun, et al.
Publicado: (2019)

Differential Modulation of TCF/LEF-1 Activity by the Soluble LRP6-ICD
por: Beagle, Brandon, et al.
Publicado: (2010)

LEF-1 and TCF4 expression correlate inversely with survival in colorectal cancer
por: Kriegl, Lydia, et al.
Publicado: (2010)

Role of TCF/LEF Transcription Factors in Bone Development and Osteogenesis
por: Li, Zhengqiang, et al.
Publicado: (2018)

TCF/LEF Transcription Factors: An Update from the Internet Resources
por: Hrckulak, Dusan, et al.
Publicado: (2016)

LEF-1 and TCF-1 orchestrate T follicular helper cell differentiation by regulating differentiation circuits upstream of Bcl6
por: Choi, Youn Soo, et al.
Publicado: (2015)

Evolutionary diversification of the canonical Wnt signaling effector TCF/LEF in chordates
por: Torres‐Aguila, Nuria P., et al.
Publicado: (2022)

Pja2 Inhibits Wnt/β-catenin Signaling by Reducing the Level of TCF/LEF1
por: Song, Yonghee, et al.
Publicado: (2018)

Depletion of Tcf3 and Lef1 maintains mouse embryonic stem cell self-renewal
por: Ye, Shoudong, et al.
Publicado: (2017)

Tcf1 and Lef1 transcription factors establish CD8(+) T cell identity through intrinsic HDAC activity
por: Xing, Shaojun, et al.
Publicado: (2016)

Tcf1 and Lef1 provide constant supervision to mature CD8(+) T cell identity and function by organizing genomic architecture
por: Shan, Qiang, et al.
Publicado: (2021)

TCF/Lef1 activity controls establishment of diverse stem and progenitor cell compartments in mouse epidermis
por: Petersson, Monika, et al.
Publicado: (2011)

VBP1 modulates Wnt/β-catenin signaling by mediating the stability of the transcription factors TCF/LEFs
por: Zhang, Haifeng, et al.
Publicado: (2021)

Past Visits Present: TCF/LEFs Partner with ATFs for β-Catenin–Independent Activity
por: Sprowl, Stephanie, et al.
Publicado: (2013)

DC-SIGN–LEF1/TCF1–miR-185 feedback loop promotes colorectal cancer invasion and metastasis
por: Yuan, Menglang, et al.
Publicado: (2019)

Different behaviour of DVL1, DVL2, DVL3 in astrocytoma malignancy grades and their association to TCF1 and LEF1 upregulation
por: Kafka, Anja, et al.
Publicado: (2018)

Nuclear LEF1/TCF4 correlate with poor prognosis but not with nuclear β-catenin in cerebral metastasis of lung adenocarcinomas
por: Bleckmann, A., et al.
Publicado: (2012)

TCF/Lef regulates the Gsx ParaHox gene in central nervous system development in chordates
por: Garstang, Myles G., et al.
Publicado: (2016)

IL-7 Receptor Signals Inhibit Expression of Transcription Factors TCF-1, LEF-1, and RORγt: Impact on Thymocyte Development
por: Yu, Qing, et al.
Publicado: (2004)

Correction to: DC-SIGN–LEF1/TCF1–miR-185 feedback loop promotes colorectal cancer invasion and metastasis
por: Yuan, Menglang, et al.
Publicado: (2021)

TCF1/LEF1 triggers Wnt-dependent chemokine/cytokine-induced inflammation and cadherin pathways to drive T-ALL cell migration
por: Zhao, Pin, et al.
Publicado: (2023)

β-Catenin-Independent Activation of TCF1/LEF1 in Human Hematopoietic Tumor Cells through Interaction with ATF2 Transcription Factors
por: Grumolato, Luca, et al.
Publicado: (2013)

Expression of transferrin receptor‐1 (TFR‐1) in canine osteosarcomas
por: De Vico, Gionata, et al.
Publicado: (2020)

Oral probiotics increased the proportion of Treg, Tfr, and Breg cells to inhibit the inflammatory response and impede gestational diabetes mellitus
por: Liang, Weijie, et al.
Publicado: (2023)

An alternative polyadenylation signal in TCF7L2 generates isoforms that inhibit T cell factor/lymphoid-enhancer factor (TCF/LEF)-dependent target genes
por: Locke, J. M., et al.
Publicado: (2011)

Opposing Roles of Tcf7/Lef1 and Tcf7l2 in Cyclin D2 and Bmp4 Expression and Cardiomyocyte Cell Cycle Control during Late Heart Development
por: Ye, Bo, et al.
Publicado: (2019)

Frontiers of Autoantibodies in Autoimmune Disorders: Crosstalk Between Tfh/Tfr and Regulatory B Cells
por: Ding, Tingting, et al.
Publicado: (2021)

Erratum to: An alternative polyadenylation signal in TCF7L2 generates isoforms that inhibit T cell factor/lymphoid-enhancer factor (TCF/LEF)-dependent target genes
por: Locke, J. M., et al.
Publicado: (2011)

Regulation of mitochondrial morphology and function by Stearoylation of TfR1
por: Senyilmaz, Deniz, et al.
Publicado: (2015)

TFR1 expression in induced sputum is associated with asthma severity
por: Wang, Yang, et al.
Publicado: (2022)

Transferrin receptor (TfR) trafficking determines brain uptake of TfR antibody affinity variants
por: Bien-Ly, Nga, et al.
Publicado: (2014)

Liver cancer: WISP3 suppresses hepatocellular carcinoma progression by negative regulation of β‐catenin/TCF/LEF signalling
por: Gao, Hong, et al.
Publicado: (2019)

TCF-1 and LEF-1 act upstream of Th-POK to promote CD4(+) T cell lineage choice and cooperate with Runx3 to silence the Cd4 gene in CD8(+) T cells
por: Steinke, Farrah C., et al.
Publicado: (2014)

Over-expression of ASIC1a promotes proliferation via activation of the β-catenin/LEF-TCF axis and is associated with disease outcome in liver cancer
por: Jin, Cheng, et al.
Publicado: (2016)

Baicalin ameliorates lupus autoimmunity by inhibiting differentiation of Tfh cells and inducing expansion of Tfr cells
por: Yang, Ji, et al.
Publicado: (2019)

Dysregulated TFR and TFH cells correlate with B‐cell differentiation and antibody production in autoimmune hepatitis
por: Liang, Ma, et al.
Publicado: (2020)

Lef1-dependent hypothalamic neurogenesis inhibits anxiety
por: Xie, Yuanyuan, et al.
Publicado: (2017)

PDL1 blockage increases fetal resorption and Tfr cells but does not affect Tfh/Tfr ratio and B-cell maturation during allogeneic pregnancy
por: Zeng, Weihong, et al.
Publicado: (2020)

Rational design of universal immunotherapy for TfR1-tropic arenaviruses
por: Cohen-Dvashi, Hadas, et al.
Publicado: (2020)

SATB2/β-catenin/TCF-LEF pathway induces cellular transformation by generating cancer stem cells in colorectal cancer
por: Yu, Wei, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_loi5in68kbtrrv0ph2nv4i6cg4