Cross-sectional study into age-related pathology of mouse models for limb girdle muscular dystrophy types 2D and 2F

Limb girdle muscular dystrophy (LGMD) types 2D and 2F are caused by mutations in the genes encoding for α- and δ-sarcoglycan, respectively, leading to progressive muscle weakness. Mouse models exist for LGMD2D (Sgca(-/-)) and 2F (Sgcd(-/-)). In a previous natural history study, we described the path...

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Detalles Bibliográficos
Autores principales: Verhaart, Ingrid E. C., Putker, Kayleigh, van de Vijver, Davy, Tanganyika-de Winter, Christa L., Pasteuning-Vuhman, Svetlana, Plomp, Jaap J., Aartsma-Rus, Annemieke M., van Putten, Maaike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701749/
https://www.ncbi.nlm.nih.gov/pubmed/31430305
http://dx.doi.org/10.1371/journal.pone.0220665

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