Conjugation of an scFab domain to the oligomeric HIV envelope protein for use in immune targeting

A promising strategy for the enhancement of vaccine-mediated immune responses is by directly targeting protein antigens to immune cells. Targeting of antigens to the dendritic cell (DC) molecule Clec9A has been shown to enhance antibody affinity and titers for model antigens, and influenza and enter...

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Detalles Bibliográficos
Autores principales: King, Hannah A. D., Gonelli, Christopher A., Tullett, Kirsteen M., Lahoud, Mireille H., Purcell, Damian F. J., Drummer, Heidi E., Poumbourios, Pantelis, Center, Rob J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701830/
https://www.ncbi.nlm.nih.gov/pubmed/31430333
http://dx.doi.org/10.1371/journal.pone.0220986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701830/
https://www.ncbi.nlm.nih.gov/pubmed/31430333
http://dx.doi.org/10.1371/journal.pone.0220986

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