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Ribosome Collisions Result in +1 Frameshifting in the Absence of No-Go Decay
During translation, an mRNA is typically occupied by multiple ribosomes sparsely distributed across the coding sequence. This distribution, mediated by slow rates of initiation relative to elongation, ensures that they rarely collide with each other, but given the stochastic nature of protein synthe...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701860/ https://www.ncbi.nlm.nih.gov/pubmed/31412239 http://dx.doi.org/10.1016/j.celrep.2019.07.046 |