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Single-Cell RNA Transcriptome Helps Define the Limbal/Corneal Epithelial Stem/Early Transit Amplifying Cells and How Autophagy Affects This Population
PURPOSE: Single-cell RNA-sequencing (scRNA-seq) was used to interrogate the relatively rare stem (SC) and early transit amplifying (TA) cell populations in limbal/corneal epithelia from wild-type and autophagy-compromised mice. METHODS: We conducted scRNA-seq on ocular anterior segmental tissue from...
Autores principales: | Kaplan, Nihal, Wang, Junyi, Wray, Brian, Patel, Priyam, Yang, Wending, Peng, Han, Lavker, Robert M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701873/ https://www.ncbi.nlm.nih.gov/pubmed/31419300 http://dx.doi.org/10.1167/iovs.19-27656 |
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