Varicella-zoster Virus Related Pulmonary Granulomas in Which Varicella-zoster Virus DNA Was Demonstrated in a Thoracoscopic Lung Biopsy Specimen

A 43-year-old man with malignant lymphoma who had been treated with the cyclosphamide, vincrstine, procarbazine, and prednisolone (C-MOPP) regimen was admitted to our hospital with skin eruption. He was diagnosed to have varicella, and treatment with acyclovir and immune globulin was started. Chest...

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Autores principales: Isobe, Takeshi, Umemoto, Jyunro, Kobayashi, Misato, Okuno, Takae, Shiratsuki, Youhei, Kodama, Akari, Nakao, Mika, Amano, Yoshihiro, Hotta, Takamasa, Hamaguchi, Megumi, Okimoto, Tamio, Hamaguchi, Shunichi, Tsubata, Yukari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702000/
https://www.ncbi.nlm.nih.gov/pubmed/30918176
http://dx.doi.org/10.2169/internalmedicine.2021-18
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author Isobe, Takeshi
Umemoto, Jyunro
Kobayashi, Misato
Okuno, Takae
Shiratsuki, Youhei
Kodama, Akari
Nakao, Mika
Amano, Yoshihiro
Hotta, Takamasa
Hamaguchi, Megumi
Okimoto, Tamio
Hamaguchi, Shunichi
Tsubata, Yukari
author_facet Isobe, Takeshi
Umemoto, Jyunro
Kobayashi, Misato
Okuno, Takae
Shiratsuki, Youhei
Kodama, Akari
Nakao, Mika
Amano, Yoshihiro
Hotta, Takamasa
Hamaguchi, Megumi
Okimoto, Tamio
Hamaguchi, Shunichi
Tsubata, Yukari
author_sort Isobe, Takeshi
collection PubMed
description A 43-year-old man with malignant lymphoma who had been treated with the cyclosphamide, vincrstine, procarbazine, and prednisolone (C-MOPP) regimen was admitted to our hospital with skin eruption. He was diagnosed to have varicella, and treatment with acyclovir and immune globulin was started. Chest computed tomography revealed multiple nodules in the both lung fields. Diagnostic thoracoscopic lung biopsy specimens revealed granuloma formation, and polymerase chain reaction testing revealed the presence of varicella-zoster virus DNA in the granulomatous tissue. It was unusual for the lung nodule in varicella pneumonia to increase in size over time in a patient who had undergone antiviral therapy, while also demonstrating multiple granulomas.
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spelling pubmed-67020002019-08-21 Varicella-zoster Virus Related Pulmonary Granulomas in Which Varicella-zoster Virus DNA Was Demonstrated in a Thoracoscopic Lung Biopsy Specimen Isobe, Takeshi Umemoto, Jyunro Kobayashi, Misato Okuno, Takae Shiratsuki, Youhei Kodama, Akari Nakao, Mika Amano, Yoshihiro Hotta, Takamasa Hamaguchi, Megumi Okimoto, Tamio Hamaguchi, Shunichi Tsubata, Yukari Intern Med Case Report A 43-year-old man with malignant lymphoma who had been treated with the cyclosphamide, vincrstine, procarbazine, and prednisolone (C-MOPP) regimen was admitted to our hospital with skin eruption. He was diagnosed to have varicella, and treatment with acyclovir and immune globulin was started. Chest computed tomography revealed multiple nodules in the both lung fields. Diagnostic thoracoscopic lung biopsy specimens revealed granuloma formation, and polymerase chain reaction testing revealed the presence of varicella-zoster virus DNA in the granulomatous tissue. It was unusual for the lung nodule in varicella pneumonia to increase in size over time in a patient who had undergone antiviral therapy, while also demonstrating multiple granulomas. The Japanese Society of Internal Medicine 2019-03-28 2019-07-15 /pmc/articles/PMC6702000/ /pubmed/30918176 http://dx.doi.org/10.2169/internalmedicine.2021-18 Text en Copyright © 2019 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Isobe, Takeshi
Umemoto, Jyunro
Kobayashi, Misato
Okuno, Takae
Shiratsuki, Youhei
Kodama, Akari
Nakao, Mika
Amano, Yoshihiro
Hotta, Takamasa
Hamaguchi, Megumi
Okimoto, Tamio
Hamaguchi, Shunichi
Tsubata, Yukari
Varicella-zoster Virus Related Pulmonary Granulomas in Which Varicella-zoster Virus DNA Was Demonstrated in a Thoracoscopic Lung Biopsy Specimen
title Varicella-zoster Virus Related Pulmonary Granulomas in Which Varicella-zoster Virus DNA Was Demonstrated in a Thoracoscopic Lung Biopsy Specimen
title_full Varicella-zoster Virus Related Pulmonary Granulomas in Which Varicella-zoster Virus DNA Was Demonstrated in a Thoracoscopic Lung Biopsy Specimen
title_fullStr Varicella-zoster Virus Related Pulmonary Granulomas in Which Varicella-zoster Virus DNA Was Demonstrated in a Thoracoscopic Lung Biopsy Specimen
title_full_unstemmed Varicella-zoster Virus Related Pulmonary Granulomas in Which Varicella-zoster Virus DNA Was Demonstrated in a Thoracoscopic Lung Biopsy Specimen
title_short Varicella-zoster Virus Related Pulmonary Granulomas in Which Varicella-zoster Virus DNA Was Demonstrated in a Thoracoscopic Lung Biopsy Specimen
title_sort varicella-zoster virus related pulmonary granulomas in which varicella-zoster virus dna was demonstrated in a thoracoscopic lung biopsy specimen
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702000/
https://www.ncbi.nlm.nih.gov/pubmed/30918176
http://dx.doi.org/10.2169/internalmedicine.2021-18
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