Crohn's Disease Accompanied with Small Intestinal Extramedullary Plasmacytoma

We herein present the case of an immunocompetent 63-year-old man who had previously undergone resection of Crohn's disease (CD)-related small intestinal obstruction more than 30 years ago. He had not been receiving any medication for many years, but had recently started to suffer from ileus. A...

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Detalles Bibliográficos
Autores principales: Hanawa, Yoshinori, Higashiyama, Masaaki, Horiuchi, Kazuki, Ayaki, Kana, Ito, Suguru, Mizoguchi, Akinori, Nishii, Shin, Wada, Akinori, Inaba, Kenichi, Sugihara, Nao, Furuhashi, Hirotaka, Takajo, Takeshi, Shirakabe, Kazuhiko, Watanabe, Chikako, Tomita, Kengo, Komoto, Shunsuke, Nagao, Shigeaki, Miura, Soichiro, Shimazaki, Hideyuki, Takeuchi, Kengo, Ueno, Hideki, Hokari, Ryota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702015/
https://www.ncbi.nlm.nih.gov/pubmed/30918171
http://dx.doi.org/10.2169/internalmedicine.1687-18
Descripción
Sumario:We herein present the case of an immunocompetent 63-year-old man who had previously undergone resection of Crohn's disease (CD)-related small intestinal obstruction more than 30 years ago. He had not been receiving any medication for many years, but had recently started to suffer from ileus. A stenosed site of ileo-cecal anastomosis was identified and therefore was surgically resected, which was diagnosed as CD with small intestinal extramedullary plasmacytoma (EMP). The subsequent progression of CD was successfully controlled by anti-TNFα agents without any recurrence of EMP for over 3 years, implying the clinical benefit and safety of the biological therapy. This was the first known case of a patient who received anti-TNFα agents after a resection of small intestinal EMP accompanied with CD.

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