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Crohn's Disease Accompanied with Small Intestinal Extramedullary Plasmacytoma
We herein present the case of an immunocompetent 63-year-old man who had previously undergone resection of Crohn's disease (CD)-related small intestinal obstruction more than 30 years ago. He had not been receiving any medication for many years, but had recently started to suffer from ileus. A...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Internal Medicine
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702015/ https://www.ncbi.nlm.nih.gov/pubmed/30918171 http://dx.doi.org/10.2169/internalmedicine.1687-18 |
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author | Hanawa, Yoshinori Higashiyama, Masaaki Horiuchi, Kazuki Ayaki, Kana Ito, Suguru Mizoguchi, Akinori Nishii, Shin Wada, Akinori Inaba, Kenichi Sugihara, Nao Furuhashi, Hirotaka Takajo, Takeshi Shirakabe, Kazuhiko Watanabe, Chikako Tomita, Kengo Komoto, Shunsuke Nagao, Shigeaki Miura, Soichiro Shimazaki, Hideyuki Takeuchi, Kengo Ueno, Hideki Hokari, Ryota |
author_facet | Hanawa, Yoshinori Higashiyama, Masaaki Horiuchi, Kazuki Ayaki, Kana Ito, Suguru Mizoguchi, Akinori Nishii, Shin Wada, Akinori Inaba, Kenichi Sugihara, Nao Furuhashi, Hirotaka Takajo, Takeshi Shirakabe, Kazuhiko Watanabe, Chikako Tomita, Kengo Komoto, Shunsuke Nagao, Shigeaki Miura, Soichiro Shimazaki, Hideyuki Takeuchi, Kengo Ueno, Hideki Hokari, Ryota |
author_sort | Hanawa, Yoshinori |
collection | PubMed |
description | We herein present the case of an immunocompetent 63-year-old man who had previously undergone resection of Crohn's disease (CD)-related small intestinal obstruction more than 30 years ago. He had not been receiving any medication for many years, but had recently started to suffer from ileus. A stenosed site of ileo-cecal anastomosis was identified and therefore was surgically resected, which was diagnosed as CD with small intestinal extramedullary plasmacytoma (EMP). The subsequent progression of CD was successfully controlled by anti-TNFα agents without any recurrence of EMP for over 3 years, implying the clinical benefit and safety of the biological therapy. This was the first known case of a patient who received anti-TNFα agents after a resection of small intestinal EMP accompanied with CD. |
format | Online Article Text |
id | pubmed-6702015 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | The Japanese Society of Internal Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-67020152019-08-21 Crohn's Disease Accompanied with Small Intestinal Extramedullary Plasmacytoma Hanawa, Yoshinori Higashiyama, Masaaki Horiuchi, Kazuki Ayaki, Kana Ito, Suguru Mizoguchi, Akinori Nishii, Shin Wada, Akinori Inaba, Kenichi Sugihara, Nao Furuhashi, Hirotaka Takajo, Takeshi Shirakabe, Kazuhiko Watanabe, Chikako Tomita, Kengo Komoto, Shunsuke Nagao, Shigeaki Miura, Soichiro Shimazaki, Hideyuki Takeuchi, Kengo Ueno, Hideki Hokari, Ryota Intern Med Case Report We herein present the case of an immunocompetent 63-year-old man who had previously undergone resection of Crohn's disease (CD)-related small intestinal obstruction more than 30 years ago. He had not been receiving any medication for many years, but had recently started to suffer from ileus. A stenosed site of ileo-cecal anastomosis was identified and therefore was surgically resected, which was diagnosed as CD with small intestinal extramedullary plasmacytoma (EMP). The subsequent progression of CD was successfully controlled by anti-TNFα agents without any recurrence of EMP for over 3 years, implying the clinical benefit and safety of the biological therapy. This was the first known case of a patient who received anti-TNFα agents after a resection of small intestinal EMP accompanied with CD. The Japanese Society of Internal Medicine 2019-03-28 2019-07-15 /pmc/articles/PMC6702015/ /pubmed/30918171 http://dx.doi.org/10.2169/internalmedicine.1687-18 Text en Copyright © 2019 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Hanawa, Yoshinori Higashiyama, Masaaki Horiuchi, Kazuki Ayaki, Kana Ito, Suguru Mizoguchi, Akinori Nishii, Shin Wada, Akinori Inaba, Kenichi Sugihara, Nao Furuhashi, Hirotaka Takajo, Takeshi Shirakabe, Kazuhiko Watanabe, Chikako Tomita, Kengo Komoto, Shunsuke Nagao, Shigeaki Miura, Soichiro Shimazaki, Hideyuki Takeuchi, Kengo Ueno, Hideki Hokari, Ryota Crohn's Disease Accompanied with Small Intestinal Extramedullary Plasmacytoma |
title | Crohn's Disease Accompanied with Small Intestinal Extramedullary Plasmacytoma |
title_full | Crohn's Disease Accompanied with Small Intestinal Extramedullary Plasmacytoma |
title_fullStr | Crohn's Disease Accompanied with Small Intestinal Extramedullary Plasmacytoma |
title_full_unstemmed | Crohn's Disease Accompanied with Small Intestinal Extramedullary Plasmacytoma |
title_short | Crohn's Disease Accompanied with Small Intestinal Extramedullary Plasmacytoma |
title_sort | crohn's disease accompanied with small intestinal extramedullary plasmacytoma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702015/ https://www.ncbi.nlm.nih.gov/pubmed/30918171 http://dx.doi.org/10.2169/internalmedicine.1687-18 |
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