Familial Mediterranean Fever with Small Bowel Stenosis

A 37-year-old man developed abdominal pain and the frequency of severe abdominal pain steadily increased to once a month. He was therefore admitted to our hospital. Abdominal CT showed bowel obstruction. It revealed transient stenosis in the small intestine. There were no symptoms such as fever or w...

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Autores principales: Kasamaki, Keita, Kusano, Chika, Ikehara, Hisatomo, Suzuki, Sho, Esaki, Mitsuru, Irie, Akira, Hayashi, Kaori, Okuno, Hiroaki, Moriyama, Mitsuhiko, Gotoda, Takuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702021/
https://www.ncbi.nlm.nih.gov/pubmed/31308342
http://dx.doi.org/10.2169/internalmedicine.2293-18
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author Kasamaki, Keita
Kusano, Chika
Ikehara, Hisatomo
Suzuki, Sho
Esaki, Mitsuru
Irie, Akira
Hayashi, Kaori
Okuno, Hiroaki
Moriyama, Mitsuhiko
Gotoda, Takuji
author_facet Kasamaki, Keita
Kusano, Chika
Ikehara, Hisatomo
Suzuki, Sho
Esaki, Mitsuru
Irie, Akira
Hayashi, Kaori
Okuno, Hiroaki
Moriyama, Mitsuhiko
Gotoda, Takuji
author_sort Kasamaki, Keita
collection PubMed
description A 37-year-old man developed abdominal pain and the frequency of severe abdominal pain steadily increased to once a month. He was therefore admitted to our hospital. Abdominal CT showed bowel obstruction. It revealed transient stenosis in the small intestine. There were no symptoms such as fever or weight loss, it seemed unlikely that the patient had inflammatory bowel disease. Considering the history of recurrent abdominal pain, Familial Mediterranean Fever (FMF) was considered. As a result, a genetic analysis revealed mutations in exons 3 and 8 of the MEFV gene. We herein report the first known case of FMF with transient small bowel stenosis in Japan.
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spelling pubmed-67020212019-08-21 Familial Mediterranean Fever with Small Bowel Stenosis Kasamaki, Keita Kusano, Chika Ikehara, Hisatomo Suzuki, Sho Esaki, Mitsuru Irie, Akira Hayashi, Kaori Okuno, Hiroaki Moriyama, Mitsuhiko Gotoda, Takuji Intern Med Case Report A 37-year-old man developed abdominal pain and the frequency of severe abdominal pain steadily increased to once a month. He was therefore admitted to our hospital. Abdominal CT showed bowel obstruction. It revealed transient stenosis in the small intestine. There were no symptoms such as fever or weight loss, it seemed unlikely that the patient had inflammatory bowel disease. Considering the history of recurrent abdominal pain, Familial Mediterranean Fever (FMF) was considered. As a result, a genetic analysis revealed mutations in exons 3 and 8 of the MEFV gene. We herein report the first known case of FMF with transient small bowel stenosis in Japan. The Japanese Society of Internal Medicine 2019-07-15 /pmc/articles/PMC6702021/ /pubmed/31308342 http://dx.doi.org/10.2169/internalmedicine.2293-18 Text en Copyright © 2019 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kasamaki, Keita
Kusano, Chika
Ikehara, Hisatomo
Suzuki, Sho
Esaki, Mitsuru
Irie, Akira
Hayashi, Kaori
Okuno, Hiroaki
Moriyama, Mitsuhiko
Gotoda, Takuji
Familial Mediterranean Fever with Small Bowel Stenosis
title Familial Mediterranean Fever with Small Bowel Stenosis
title_full Familial Mediterranean Fever with Small Bowel Stenosis
title_fullStr Familial Mediterranean Fever with Small Bowel Stenosis
title_full_unstemmed Familial Mediterranean Fever with Small Bowel Stenosis
title_short Familial Mediterranean Fever with Small Bowel Stenosis
title_sort familial mediterranean fever with small bowel stenosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702021/
https://www.ncbi.nlm.nih.gov/pubmed/31308342
http://dx.doi.org/10.2169/internalmedicine.2293-18
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