Cargando…

Descriptive assessment of rabies post-exposure prophylaxis procurement, distribution, monitoring, and reporting in four Asian countries: Bangladesh, Bhutan, Cambodia, and Sri Lanka, 2017–2018

BACKGROUND: There are approximately 35,000 human deaths from rabies in Asia annually. Rabies can be prevented through timely post-exposure prophylaxis (PEP) consisting of wound washing, rabies vaccine, and in some cases, rabies immunoglobulin (RIG). However, access to rabies PEP often remains limite...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Anyie J., Sreenivasan, Nandini, Siddiqi, Umme Ruman, Tahmina, Sanya, Penjor, Kinley, Sovann, Ly, Gunesekera, Amila, Blanton, Jesse D., Knopf, Lea, Hyde, Terri B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702106/
https://www.ncbi.nlm.nih.gov/pubmed/30314908
http://dx.doi.org/10.1016/j.vaccine.2018.10.011
_version_ 1783445157054513152
author Li, Anyie J.
Sreenivasan, Nandini
Siddiqi, Umme Ruman
Tahmina, Sanya
Penjor, Kinley
Sovann, Ly
Gunesekera, Amila
Blanton, Jesse D.
Knopf, Lea
Hyde, Terri B.
author_facet Li, Anyie J.
Sreenivasan, Nandini
Siddiqi, Umme Ruman
Tahmina, Sanya
Penjor, Kinley
Sovann, Ly
Gunesekera, Amila
Blanton, Jesse D.
Knopf, Lea
Hyde, Terri B.
author_sort Li, Anyie J.
collection PubMed
description BACKGROUND: There are approximately 35,000 human deaths from rabies in Asia annually. Rabies can be prevented through timely post-exposure prophylaxis (PEP) consisting of wound washing, rabies vaccine, and in some cases, rabies immunoglobulin (RIG). However, access to rabies PEP often remains limited to urban areas and is cost-prohibitive. There is little information on procurement, distribution, monitoring, and reporting of rabies PEP. METHODS: We interviewed key informants in the public sector from various levels in Bangladesh, Bhutan, Cambodia, and Sri Lanka between March 2017 and May 2018 using a descriptive assessment tool to obtain information on procurement, distribution, monitoring, and reporting of rabies PEP. These four countries in Asia were chosen to showcase a range of rabies PEP systems. National rabies focal points were interviewed in each country and focal points helped identify additional key informants at lower levels. RESULTS: A total of 22 key informants were interviewed at various levels (central level to health facility level) including national rabies focal points in each country. Each country has a unique system for managing rabies PEP procurement, distribution, monitoring, and reporting. There are varying levels of PEP access for those with potential rabies exposures. Rabies PEP is available in select health facilities throughout the country in Bangladesh, Bhutan, and Sri Lanka. In Cambodia, rabies PEP is limited to two urban centers. The availability of RIG in all four countries is limited. In these four countries, most aspects of the rabies PEP distribution system operate independently of systems for other vaccines. However, in Bhutan, rabies PEP and Expanded Programme on Immunization (EPI) vaccines share cold chain space in some locations at the lowest level. All countries have a monitoring system in place, but there is limited reporting of data, particularly to the central level. CONCLUSION: Systems to procure, deliver, monitor, and report on rabies PEP are variable across countries. Sharing information on practices more widely among countries can help programs to increase access to this life-saving treatment.
format Online
Article
Text
id pubmed-6702106
institution National Center for Biotechnology Information
language English
publishDate 2018
record_format MEDLINE/PubMed
spelling pubmed-67021062019-10-03 Descriptive assessment of rabies post-exposure prophylaxis procurement, distribution, monitoring, and reporting in four Asian countries: Bangladesh, Bhutan, Cambodia, and Sri Lanka, 2017–2018 Li, Anyie J. Sreenivasan, Nandini Siddiqi, Umme Ruman Tahmina, Sanya Penjor, Kinley Sovann, Ly Gunesekera, Amila Blanton, Jesse D. Knopf, Lea Hyde, Terri B. Vaccine Article BACKGROUND: There are approximately 35,000 human deaths from rabies in Asia annually. Rabies can be prevented through timely post-exposure prophylaxis (PEP) consisting of wound washing, rabies vaccine, and in some cases, rabies immunoglobulin (RIG). However, access to rabies PEP often remains limited to urban areas and is cost-prohibitive. There is little information on procurement, distribution, monitoring, and reporting of rabies PEP. METHODS: We interviewed key informants in the public sector from various levels in Bangladesh, Bhutan, Cambodia, and Sri Lanka between March 2017 and May 2018 using a descriptive assessment tool to obtain information on procurement, distribution, monitoring, and reporting of rabies PEP. These four countries in Asia were chosen to showcase a range of rabies PEP systems. National rabies focal points were interviewed in each country and focal points helped identify additional key informants at lower levels. RESULTS: A total of 22 key informants were interviewed at various levels (central level to health facility level) including national rabies focal points in each country. Each country has a unique system for managing rabies PEP procurement, distribution, monitoring, and reporting. There are varying levels of PEP access for those with potential rabies exposures. Rabies PEP is available in select health facilities throughout the country in Bangladesh, Bhutan, and Sri Lanka. In Cambodia, rabies PEP is limited to two urban centers. The availability of RIG in all four countries is limited. In these four countries, most aspects of the rabies PEP distribution system operate independently of systems for other vaccines. However, in Bhutan, rabies PEP and Expanded Programme on Immunization (EPI) vaccines share cold chain space in some locations at the lowest level. All countries have a monitoring system in place, but there is limited reporting of data, particularly to the central level. CONCLUSION: Systems to procure, deliver, monitor, and report on rabies PEP are variable across countries. Sharing information on practices more widely among countries can help programs to increase access to this life-saving treatment. 2018-10-09 2019-10-03 /pmc/articles/PMC6702106/ /pubmed/30314908 http://dx.doi.org/10.1016/j.vaccine.2018.10.011 Text en This is an open access article under the CC BY IGO license. (http://creativecommons.org/licenses/by/3.0/igo/).
spellingShingle Article
Li, Anyie J.
Sreenivasan, Nandini
Siddiqi, Umme Ruman
Tahmina, Sanya
Penjor, Kinley
Sovann, Ly
Gunesekera, Amila
Blanton, Jesse D.
Knopf, Lea
Hyde, Terri B.
Descriptive assessment of rabies post-exposure prophylaxis procurement, distribution, monitoring, and reporting in four Asian countries: Bangladesh, Bhutan, Cambodia, and Sri Lanka, 2017–2018
title Descriptive assessment of rabies post-exposure prophylaxis procurement, distribution, monitoring, and reporting in four Asian countries: Bangladesh, Bhutan, Cambodia, and Sri Lanka, 2017–2018
title_full Descriptive assessment of rabies post-exposure prophylaxis procurement, distribution, monitoring, and reporting in four Asian countries: Bangladesh, Bhutan, Cambodia, and Sri Lanka, 2017–2018
title_fullStr Descriptive assessment of rabies post-exposure prophylaxis procurement, distribution, monitoring, and reporting in four Asian countries: Bangladesh, Bhutan, Cambodia, and Sri Lanka, 2017–2018
title_full_unstemmed Descriptive assessment of rabies post-exposure prophylaxis procurement, distribution, monitoring, and reporting in four Asian countries: Bangladesh, Bhutan, Cambodia, and Sri Lanka, 2017–2018
title_short Descriptive assessment of rabies post-exposure prophylaxis procurement, distribution, monitoring, and reporting in four Asian countries: Bangladesh, Bhutan, Cambodia, and Sri Lanka, 2017–2018
title_sort descriptive assessment of rabies post-exposure prophylaxis procurement, distribution, monitoring, and reporting in four asian countries: bangladesh, bhutan, cambodia, and sri lanka, 2017–2018
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6702106/
https://www.ncbi.nlm.nih.gov/pubmed/30314908
http://dx.doi.org/10.1016/j.vaccine.2018.10.011
work_keys_str_mv AT lianyiej descriptiveassessmentofrabiespostexposureprophylaxisprocurementdistributionmonitoringandreportinginfourasiancountriesbangladeshbhutancambodiaandsrilanka20172018
AT sreenivasannandini descriptiveassessmentofrabiespostexposureprophylaxisprocurementdistributionmonitoringandreportinginfourasiancountriesbangladeshbhutancambodiaandsrilanka20172018
AT siddiqiummeruman descriptiveassessmentofrabiespostexposureprophylaxisprocurementdistributionmonitoringandreportinginfourasiancountriesbangladeshbhutancambodiaandsrilanka20172018
AT tahminasanya descriptiveassessmentofrabiespostexposureprophylaxisprocurementdistributionmonitoringandreportinginfourasiancountriesbangladeshbhutancambodiaandsrilanka20172018
AT penjorkinley descriptiveassessmentofrabiespostexposureprophylaxisprocurementdistributionmonitoringandreportinginfourasiancountriesbangladeshbhutancambodiaandsrilanka20172018
AT sovannly descriptiveassessmentofrabiespostexposureprophylaxisprocurementdistributionmonitoringandreportinginfourasiancountriesbangladeshbhutancambodiaandsrilanka20172018
AT gunesekeraamila descriptiveassessmentofrabiespostexposureprophylaxisprocurementdistributionmonitoringandreportinginfourasiancountriesbangladeshbhutancambodiaandsrilanka20172018
AT blantonjessed descriptiveassessmentofrabiespostexposureprophylaxisprocurementdistributionmonitoringandreportinginfourasiancountriesbangladeshbhutancambodiaandsrilanka20172018
AT knopflea descriptiveassessmentofrabiespostexposureprophylaxisprocurementdistributionmonitoringandreportinginfourasiancountriesbangladeshbhutancambodiaandsrilanka20172018
AT hydeterrib descriptiveassessmentofrabiespostexposureprophylaxisprocurementdistributionmonitoringandreportinginfourasiancountriesbangladeshbhutancambodiaandsrilanka20172018